【作者】 王玉； 王畅； 王轶卓； 姚程； 李薇；

【机构】 吉林大学第一附属医院肿瘤中心；

【摘要】 ω-3脂肪乳剂主要是指从鱼油里提取所得的一种活性物质,其有效成分为ω-3脂肪酸,属多不饱和脂肪酸(polyunsaturated fatty acid,PUFA),包括二十碳五烯酸(eicosapentaenoic acid,EPA)、二十二碳六烯酸(docosahexaenoic acid,DHA)和α-亚麻酸。近年来,ω-3脂肪乳剂在恶性肿瘤患者中的应用越来越广泛,其抗肿瘤、减轻炎性反应、调节免疫等可能的疗效已受到广泛关注,目前,许多研究已证实其抗肿瘤及协同抗肿瘤的疗效,但也有研究认为ω-3脂肪乳剂对于恶性肿瘤患者并未表现出明显获益。其可能的抗肿瘤作用机理及协同抗肿瘤治疗效果值得我们深入探讨。更多还原

【Abstract】 Omega-3 fat emulsion mainly refers to active substances extracted from fish oil,and its effective component is omega-3 fatty acid,which belongs to the polyunsaturated fatty acids(PUFA),including eicosapentaenoic acid(EPA),docosahexaenoic acid(DHA),and alpha linolenic acid.In recent years,omega-3 fat emulsion is applicated more and more widly in the patients with malignant tumor.Its curative effects in anti-tumor,reducing inflammatory reaction,immune regulation have attracted much attention.At present,many studies have confirmed its curative effects in anti-tumor and synergistic anti-tumor.But many researches discover that applying omega-3 fat emulsion in malignant tumor patients does not show obvious benefits.Its possible antitumor mechanism and anti-tumor treatment effect is worth our further discussion.更多还原