【作者】 周方芳； 王畅； 王轶卓； 姚程； 李薇；

【机构】 吉林大学第一附属医院肿瘤中心；

【摘要】 化疗是恶性肿瘤系统治疗的重要组成部分,常常引起明显的毒性反应,尤其是骨髓抑制及胃肠道反应如恶心呕吐,会严重削弱患者的食欲,加重恶性肿瘤患者的营养不足,影响治疗及预后。近年来许多研究证明,谷氨酰胺作为一种营养物质,在恶性肿瘤患者化疗过程中起着重要的作用。多项研究表明谷氨酰胺可改善机体营养状况、增强机体的免疫功能,增加化疗的疗效、减轻化疗过程中的不良反应及提高患者的生存质量。更多还原

【Abstract】 chemotherapy is an important part of the system in treating malignant tumors and often cause obvious toxicity reaction,especially bone marrow suppression and gastrointestinal reactions such as nausea and vomiting,it will severely weakened the patient’s appetite and increase malnutrition in patients with malignant tumor,treatment and prognosis.In recent years,many studies have demonstrated that glutamine as a kind of nutrients plays an important role in the process of chemotherapy in patients with malignant tumor.A number of studies have shown that glutamine can improve the body’s nutritional status,enhance the body’s immune function,increase the curative effect of chemotherapy,alleviate the adverse reaction in the process of chemotherapy and improve the quality of life of patients.更多还原