【作者】 汪洪武； 刘艳清； 韦寿莲； 陈婉芳； 王妍雪；

【Author】 Hongwu Wang;Yanqing Liu;Shoulian Wei;Wanfang Chen;Ynaxue Wang;School of Chemistry & Chemical Engineering, Zhaoqing University;

【机构】 肇庆学院化学化工学院；

【摘要】 以双氰胺为模板分子、3-(三甲氧基硅基)丙基丙烯酸酯修饰的介孔硅为载体,甲基丙烯酸为功能单体、乙二醇二甲基丙烯酸酯为交联剂,制得对双氰胺具有特异选择性的表面分子印迹聚合物(MIP)。采用扫描电镜观察了分子印迹材料表面,用红外光谱对分子印迹材料的化学结构进行表征。静态法研究分子印迹材料对双氰胺的结合性能与分子识别特性。研究了MIP对奶粉中双氰胺方法富集、分离效果,建立了固相萃取-HPLC法检测奶粉中双氰胺的含量。结果表明,MIP具有球形附聚物、多孔的表面(见图1),对双氰胺的最大静态吸附容量分别为2.5 mg/g(见图2)。在优化的实验条件下,双氰胺的检出限(S/N=3)达到为0.00008 mg/mL。样品加标回收率为85.2~105.3%,相对标准偏差(RSD)为2.3~3.3%。所建立的方法的专属性、准确性、重现性较好。更多还原

【Abstract】 A novel molecularly imprinted polymer(MIP),which has a specific selectivity to dicyandiamide,was synthesized using dicyandiamide as template, 3-(trimethoxysilyl) propyl acrylate modified mesoporous silica as carrier, methacrylic acid as functional monomer, and thylene glycol dimethylacrylate(EGDMA) as cross-linker, respectively. The morphology of MIP was observed by SEM,and the chemical structure of MIP was characterized by FT-IR. Static method was adopted to study the binding properties and molecule recognition characters of MIP for dicyandiamide. The MIP showed the agglomerates of globular particles and porous surface morphologies. The maximum static adsorption capacities of MIP for dicyandiamide were 2.5 mg/g. The method of magnetic solid-phase extraction–HPLC was developed to determine the contents of dicyandiamide in power milks with recovery rates ranging from 85.2% to 105.3%.更多还原