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几种天然植物提取物抑制酪氨酸酶活性的研究

Study on Inhibitory Effect of Extracts from Several Plants on Tyrosinase Activity

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【作者】 曹伟伟朱晓娜李明静

【Author】 Weiwei CAO,Xiaona ZHU,Mingjing LI 1 College of Chemistry and Chemical Engineering,Henan University,Kaifeng 475004 2 Key Lab of Natural Drug and Lmmune Engineering,Henan Province,Kaifeng 475004

【机构】 河南大学化学化工学院河南大学河南省天然药物与免疫工程重点实验室

【摘要】 <正>本文考察了1%丙三醇、1%吐温-80、0.5%丙三醇和0.5%吐温-80、1%丙三醇和1%吐温-80、二次水、甲醇、乙醇、DMSO等溶剂体系,用Vc做阳性对照物,采用分光光度法测定不同浓度的茶多酚、丹皮酚和

【Abstract】 The solvent systems of 1% propanetriol,1% tween-80,0.5% propanetriol-0.5% tween-80,1% propanetriol-1% tween-80,doubledistilled water,methanol,ethanol and DMSO etc,were investigated in this paper.The effect of different concentration of tea polyphenols,paeonol and honeysuckle leaves(ethyl acetate phase) on tyrosinase activity in appropriate solvent were determined with spectrophotometry using Vc as positive control.The results indicated that 1% propanetriol and 1% tween-80 can increase the solubility of the paeonol and extracts of honeysuckle leaves significantly.These extracts all have inhibitory effect on tyrosinase activity to some degree.The consequence of the inhibitory from strong to weak was as follows: Vc、Vc: paeonol(the ratio is mass ratio)=1:2、 Vc: paeonol(the ratio is mass ratio)=1:1、tea polyphenol、tea polyphenol: paeonol(the ratio is mass ratio)=2:1、 paeonol、honeysuckle leaves extracts.The results indicated that these extracts may have a potential application value in skin cosmetic research.

  • 【会议录名称】 中国化学会第28届学术年会第9分会场摘要集
  • 【会议名称】中国化学会第28届学术年会
  • 【会议时间】2012-04-13
  • 【会议地点】中国四川成都
  • 【分类号】R285
  • 【主办单位】中国化学会
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