Application of Asymmetric Catalysis Methodology in the Synthesis of Unnatural Peptides

【作者】 王锐；

【Author】 (Rui Wang)~* State Key Laboratory of Applied Organic Chemistry,Key Laboratory of Preclinical Study for New Drugsof Gansu Province,School of Medicine,Institute of Biochemistry and Molecular Biology,School of Life Sciences,Lanzhou University,730000

【机构】 State Key Laboratory of Applied Organic Chemistry,Key Laboratory of Preclinical Study for New Drugsof Gansu Province,School of Medicine,Institute of Biochemistry and Molecular Biology,School of Life Sciences；

【摘要】 <正>Recently,the chemistry of peptide has attracted considerable interest and witnessed significant progress. As peptides exist extensively in biologically active natural products and pharmaceutical compounds,the development of peptide or peptide-mimetic ligands is no doubt one of the most extensive areas of biology and medicine.However,peptides usually suffer from serious limitations including short duration of action,更多还原