【作者】 李晓坤； 张华锋； 董晶晶； 杨云；

【Author】 Li Xiao-kun Zhang Hua-feng Dong Jing-jing Yang Yun (Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China)

【机构】 河南中医学院；

【摘要】 目的研究首乌藤多糖对小鼠免疫活性的影响方法采用正常小鼠模型和小鼠免疫抑制模型,以生理盐水为空白对照组,香菇多糖为阳性对照组,灌服首乌藤多糖,观察对小鼠腹腔巨噬细胞吞噬功能的影响及溶血素和溶血空斑形成的影响。结果与空白对照组相比,首乌藤多糖组可显著提高正常小鼠和免疫低下小鼠腹腔巨噬细胞对鸡红细胞的吞噬百分率和吞噬指数,促进溶血素和溶血空斑的形成,其中以0.2g/kg首乌藤多糖剂量组作用为最佳。结论实验研究表明首乌藤多糖具有明显的免疫增强作用,值得深入研究更多还原

【Abstract】 Objiective Study the influence of polysaccharides from Caulis Polygoni Multiflori on immune function of mice.Methods Use normal and immunosuppression mice model;the physiological saline for blank control group,the lentinan for positive control group;gabage Caulis Polygoni Multiflori and observe its influence on phagocytic function of murine peritoneal macrophages and the formation of hemolysin and hemolytic plaque.Results Caulis Polygoni Multiflori can significantly improve the macrophage phagocytic percentage and phagocytic index of normal and immunosuppression mice compared with blank control group,promote the formation of hemolysin and hemolytic plaque,of which 0.2 g/kg dose group of polysaccharides has best effect.Conclusion Pharmacology experiment research shows that the Caulis Polygoni Multiflori polysaccharides have obvious immunoenhancement and deserve in-depth research更多还原