【作者】 王金萍； 窦明金； 黄桂华；

【Author】 Wang Jinpin 1,DOU Ming-jin 2,Huang Guihua 1 (1.College of Pharmacy,Shandong University,Jinan 250012 China;2.The department of pharmacy,shandong province tumour hospital,Jinan 250014 China)

【机构】 山东大学药学院； 山东省肿瘤医院；

【摘要】 抗菌药物的广泛应用使细菌耐药性不断增加,微粒给药系统的应用可以改善药物的生物利用度、降低毒副作用,提高药物的靶向性和治疗效果。本文综合国内外相关文献,介绍脂质体、纳米粒、微球等新型微粒给药系统在抗菌药中的应用。更多还原

【Abstract】 As the extensive use of antibiotics,the drug resistance of bacteria grows continually.Application of particulate delivery system can improve drug bioavailability,depress toxic and side-effect and raise the targeting and treatment effectiveness.This article comprehended pertinent literatures,to introduce the application in antimicrobial of particulate delivery system such as liposome,nanoparticle,microsphere,and so on.更多还原