【作者】 任凤霞； 乔善义； 赵毅民； 齐春会； 张永祥；

【Author】 REN Feng-xia,Qiao Shan-yi,ZHAO Yi-min,QI Chun-hui,ZHANG Yong-xiang (Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences,Beijing 100850)

【机构】 军事医学科学院毒物药物研究所；

【摘要】 目的:研究六味地黄汤中部分多糖组分的化学结构特征。方法:采用DEAE-纤维素柱色谱和凝胶渗透色谱分离纯化,化学和光谱方法分析其结构特征。结果:从六味地黄水提取物中分离得到3个均一多糖组分LWP2-1,LWP2-2和LWP2-3,其相对分子量分别为7.46×10~4,5.51×10~4和4.07×10~4,主要由鼠李糖,阿拉伯糖,葡萄糖,半乳糖和半乳糖醛酸组成。结论:3种多糖为首次从六味地黄中分得,均为结构复杂的杂多糖。更多还原

【Abstract】 Objective To study the structural feature of some polysaccharides from Liuweidihuang decoction.Methods DEAE-cellulose and gel-filtration chromatography were used to isolate and purify the polysaccharides.Their structures were investigated using chemical and spectral methods.Results Three homogeneous polysaccharides,named LWP2-1,LWP2-2 and LWP2-3,were obtained from Liuweidihuang decoction.They were composed of Rha,Ara,Glc,Gal and GalA and have molecular weights of 7.46×10~4,5.51×10~4 and 4.07×10~4,respectively.Conclusion These three polysaccharides and were obtained from Liuweidihuang decoction for the first time and are complex hetero-polysaccharide.更多还原