【作者】 杨思芸； 张健；

【Author】 YANG Si-yun 1,ZHANG Jian 2 (1.Pharmacy Department of Nanchong Centeral Hospital Nanchong 637000,China;2.Clinical Inspection Department of Nanchong Central Hospital,Nanchong 637000,China)

【机构】 南充市中心医院药剂科； 南充市中心医院检验科；

【摘要】 目的总结我院临床送检标本中分离到的35株嗜麦芽窄食单胞菌的感染分布与耐药情况,为预防和治疗该菌感染提供依据。方法按常规方法培养分离住院患者送检的痰液、胸水等标本;采用法国生物梅里埃公司生产的VITEK-32全自动微生物鉴定及药敏系统对进行菌株鉴定和药敏试验;药敏结果判定符合CLSI标准。结果嗜麦芽窄食单胞菌主要分布在重症监护病房(ICU)和呼吸内科,主要来自痰标本(91.4%),对左氧氟沙星、复方新诺明、环丙沙星的耐药率分别为29.4%、51.4%、71.4%,对其他17种所试抗菌药物的耐药率均高达90%以上。结论我院嗜麦芽窄食单胞菌耐药情况严峻,控制感染发生的关键在于减少不合理抗菌药物的应用。更多还原

【Abstract】 OBJECTIVE To summarize the distribution of Thirty-five strains of Stenotrophomonas maltophilia infection and its antibiotic-resistance characteristics,provideing basis to prevent and treat the infection of Stenotrophomonas maltophilia.METHODS To cultivate and separate the sputum、hydrothorax from hospitalized patients by general methods,and identified by VITEK-32 System of drug-susceptibility.The results were assessed with CLSI.RESULTS Stenotrophomonas maltophilia strains were mainly distributed in the ICU ward and department of respiration,The highest appearing rate was the sputum(91.4 %),the resistance rates to Levofloxacin、compound sulfamethoxazole、Ciprofloxacin were 29.4% 、51.4%、71.4%,the resistance rates of the other 17 tested antibiotics were more than 90%.CONCLUSION The case of the antibiotic-resistant of Stenotrophomonas maltophilia in our hospital was serious,the key to control the infection was to lessen unreasonable use of antibiotics.更多还原