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水芹总酚酸对正常小鼠免疫功能的影响
Effects of Total Phenolics Acid Extracted from Oenan the Javanica on Immune Function in Normal Mice
【Author】 ZHANG Wei,HUANG Zheng-ming,CHEN Xiao-nong
【机构】 北京化工大学材料科学与工程学院; 解放军302医院药学部临床药理研究室;
【摘要】 目的 :探讨水芹总酚酸对正常小鼠的免疫功能的影响。方法 :用分光光度计测定血清溶血素含量,MTT法检测T淋巴细胞增殖功能及ELISA法测定上清中IL-2的含量,碳粒廓清法测定碳粒廓清指数。结果 :水芹总酚酸能够显著提高血清溶血素水平及血清IL-2水平,促进ConA诱的T淋巴细胞增殖,提高正常小鼠碳粒廓清指数。结论 :水芹总酚酸对正常小鼠的免疫功能具有增强作用。
【Abstract】 Objective:To investigate the effects of Total Phenolics Acid Extracted from Oenan the Javanica(OJTPA) on immune function in normal mice.Methods:The Content of serum hemolysin was determined by spectrophotography,T-lymphocyte transformations capacity was tested by MTT,IL-2 level in the serum was measured by ELISA and the clearance rate of charcoal particles was measured through Carbon Particle Clearance.Results:Total Phenolics Acid Extracted from Oenan the Javanica(OJTPA) can markedly increase the contents of serum hemolysin and IL-2 in the serum,promote proliferative response of splenic T-lymphocyte induced by ConA and improve the clearance rate of charcoal particles.Conclusion:Total Phenolics Acid Extracted from Oenan the Javanica(OJTPA) could enhance immune function of in normal mice.
【Key words】 Total Phenolics Acid Extracted from Oenan the Javanica(OJTPA); immune function; normal mice;
- 【会议录名称】 中国医药教育论坛-中国医药教育协会第三届三次理事大会暨学术年会论文专辑
- 【会议名称】中国医药教育论坛-中国医药教育协会第三届三次理事大会暨学术年会
- 【会议时间】2013-11-10
- 【会议地点】中国重庆
- 【分类号】R285.5
- 【主办单位】中国医药教育协会(China Medicine Education Association)