【作者】 时鹏； 王文静；

【机构】 安徽省立医院神经内科；

【摘要】 【目的】探讨简易智能状态量表(MMSE)和蒙特利尔认知评估量表(MoCA)联合测评阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者轻度认知功能障碍(MCI)可行性及敏感性。【方法】应用MMSE和MoCA分别测评58例OSAHS患者和56例对照组患者。【结果】OSAHS组MMSE、MoCA评估结果和对照组相比,两组间的差异有统计学意义(P<0.05),两组在注意力、记忆力MoCA评分间的差异也有统计学意义。【结论】MMSE和MoCA联合应用可能有利于早期发现OSAHS患者的MCI,MoCA在可行性和局部认知领域缺损敏感性测评优于MMSE,可能为OSAHS患者认知障碍的早期发现、防治提供无创性筛选依据。更多还原

【Abstract】 [Otbjective]To explore the feasibility and sensitivity of the combination effect on cognitive assessment of mini-mental state examination(MMSE) and Montreal Cognitive Assessment(MoCA) in patients with obstructive sleep apnea-hypopnea syndrome(OSAHS). [Methods]Fifty-eight cases of OSAHS patients and 56 healthy control cases were included and the scores were evaluated using MMSE and(MoCA).Results There are significant differences between the OSAHS group and the healthy group(P<0.05) and MoCA showed more sensitive on attenion and recall(P<0.05,respectively). [Conclusion]MMSE and the MoCA may be combined to detect the cognitive impairment in patients with OSAHS early.MoCA showed a more sensitivity than MMSE for the detection of frontal executive functioning and attentionm and should be a non-invasive screening tool for clinical prevention and treatment early.更多还原