【作者】 董琳； 刘明生； 王金辉； 张蕾； 沈硕； 张小坡；

【Author】 DONG Lin~1,LIU Ming-sheng~2,WANG Jin-hui~3.ZHANG lei~3,SHEN shuo~3,ZHANG xiao-po~1 (1.Faculty of Pharmacy,Hainan Medical College,Haikou 571101,China). (2.Academy of South medicine and Li medicine of Hainan Provice,Haikou 571101,China.) (3.School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China;)

【机构】 海南医学院药学院； 海南省南药黎药研究院； 沈阳药科大学中药学院；

【摘要】 目的研究裸花紫珠[Callicarpa nudifloraHook.Et Arn.]叶的化学成分。方法采用硅胶柱色谱和Sephadex LH-20柱色谱等分离化合物,运用理化性质和波谱技术确定所得化合物的结构。结果从裸花紫珠叶的氯仿萃取部位中分离得到6个已知化合物,分别鉴定为:7a-Hydroxysandaracopimaric acid(1)、香草醛(2)、5,4′-二羟基-3,7,3′-三甲氧基黄酮(3 )、5-羟基-3,7,3′,4′-四甲氧基黄酮(4)、熊果酸(5)、β-谷甾醇(6)。结论化合物2为首次从该植物中分离得到。更多还原

【Abstract】 Aim To study the chemical constituents of the leaves of Callicarpa nudiflora Hook.Et Am.Methods Compounds were isolated by column chromatography on silica gel and Sephadex LH-20 et al,and their structures were identified by physicochemical and spectral data.Results Six compounds were obtained and identified as 7α-Hydroxysandaracopimaric acid(l).vanillin(2).5.4’-dihydroxy-3,7,3’-trimethoxyflavone(3),5-hydroxy-3.7,3’.4’- tctramethoxyflavone(4).,ursolic acid(5).β-sitosterol(6).Conclusions Compounds 2 were isolated from this plant for the first time.更多还原