【作者】 熊尧； 张莉； 彭疼疼； 杨展澜； 翁诗甫； 吴瑾光；

【Author】 XIONG Yao,ZHANG Li,PENG Teng-teng,YANG Zhan-lan~*,WENG Shi-fu,WU Jin-guang State Key Laboratory of Rare Earth Materials Chemistry and Applications,College of Chemistry and Molecular Engineering,Peking University,Beijing 100871,China

【机构】 北京大学化学与分子工程学院,稀土材料与应用国家重点实验室；

【摘要】 通过pH滴定曲线、FTIR和QELS研究了pH对鹅脱氧胆酸钠聚集形态的影响。更多还原

【Abstract】 As the predominant ingredients of bile,bile salts is one of the most important bio-surfactants in vivo.In gallbladder,bile salts exist mainly as simple micelles or mixed micelles formed with phospholipid and cholesteral.Therefore,it is important to study the influence of pH on aggregation of bile salts.The aim of this paper is to examine the change of sodium chenodeoxycholate（NaCDC） aggregation by pH titration,FTIR and QELS spectroscopies.The results indicated that with addition of H⁺ into NaCDC aqueous solution above the C.M.C.,the protonated micelles were connected each other by the strong H-bond with the acid salts mode and the bigger mixed micelles were formed.Finally,the gel-like H_nNa_m（CDC）_n+m was precipitated.更多还原