【作者】 王晶； 王东； 兰清昭；

【Author】 Wang Jing,Wang Dong and Lan Qinzhao (Analysis and Testing Center,Sichuan Normal University)

【机构】 四川师范大学分析测试中心；

【摘要】 <正>押。钙.钠.镁。铜。钴。镍.锌.铁.锰等称为○生命金属",它们在生命活动中起作重要作用.主族与过渡金属离子由于构型不同,所以表现的活性作用方式也不同,过渡金属的活性主要通过形成配位化合物的形式而表现出来。氨基酿是构成蛋白质的基本单位.是生命活动的主体,过渡金属与氨基酸.蛋白质的作用是生物化学上一种十分重要的作用,很多酶的活性就是通过这种作用而表现出来的,因此系统研究生命过渡金属与氨基酸的作用对研究酶等蛋白活性,建立合适的模型化合物有重要指导意义.本文用电子更多还原

【Abstract】 K,Ca,Na,Mg,Fe,Co,Ni,Cu,Zn,Mn are called metal of lif e.Tranai t ion metal has different action conduct from group A metal in life,it mainly form complex.The coordination action between transition metal and amino acid is very importment in biochemistry,such as the active of emzye is show by this kind of action.Therefore systemly study the action between transition metal o-f li-fe and amino acid has an irnportment affect for study of active of emzye and set up a suitable model compound. Results show,amino acid coordination with transition metal of life is not a single model.Serine,Glycine and Aspartic acid coordinate with transition metal of life have the same model,they all with∝-NH2 and COOH as ligand form complex.The side chain OH of serine doesn’t react.The complex of transition metal of life with Argine and Histidine have the similar spectra which similar to that of Diamine ethylene. In this case,the side chain group of amino acid take part in react as ligand,but COOH doesn’t react.All above illustrate isolate amino acid coordinate with transition metal of- life is not the same conduct that∝-NH2 and COOH as ligand. meanwhile except the coordinate model of Fe³⁺,Co²⁺react with Hisditine and Argine change with concentrate of amino acid change,others don’t.更多还原