【作者】 王锦瑜； 汪涛； 王曼； 来学惠； 李雷； 陈楚莹； 何彬洪；

【Author】 WANG Jin-yu,WANG tao,WANG man,et al.Zhongshan Center for Disease Control and prevention,Zhongshan 528400,Guangdong,China

【机构】 中山市疾病预防控制中心；

【摘要】 目的获得中山市男男性行为人群(men who have sex with men,MSM) HIV感染率及其影响因素。方法 2010年,采用同伴推动抽样法(respondent-driven sampling,RDS)招募MSM进行面对面的问卷调查,调查内容包括人口学特征、艾滋病相关知识、艾滋病相关行为和流动性;采集血样进行人类免疫缺陷病毒(HIV)、丙型肝炎病毒(HCV)和梅毒抗体检测;利用RDS分析软件(RDSAT)进行权重处理和双变量分析,SPSS进行多因素分析。结果经过10周,共招募和访谈135名MSMo高中及以上学历占75%;艾滋病知晓率91.3%;最近6个月肛交时,53.6%每次使用安全套。HIV抗体阳性18例(13.3%),HCV抗体阳性2例(1.5%),梅毒TRUST阳性11例(8.1%)0经RDSAT校正后,中山市MSM HIV,HCV和梅毒TRUST阳性率分别为15.1%(95%CI:7.3%^’25.6%)、3.0%(95%CI:0-4.2%)和8.9%(95%CI:3.3%^’ 17.5%)。多因素Logistic回归模型提示,最近6个月肛交非每次使用安全套(AOR=10.19,95%CI:2.14^-48.67),最近1年未做过HIV检测(AOR二巧.09,95%CI:1.88- 120.98)是HIV感染的危险因素。结论中山市MSM HIV感染率高,高危行为普遍存在,堕需采取针对性的干预措施。更多还原

【Abstract】 Objectives To explore the prevalence of human immunodeficiency virus(HIV) and its correlates among men who have sex with men(MSM) in Zhongshan city.Methods In 2010 respondent driven sampling(RDS) was applied to recruit MSM in Zhongshan city.A structured questionnaire was used for a face to face interview.The survey content included demographic characteristics,HIV/AIDS related knowledge,risk behaviors,and mobility.Intravenous blood samples were collected for the measurement of HIV,hepatitis C virus(HCV) and syphilis antibodies. RDS analysis tool(RDSAT) was applied for adjusting the estimates and bivariate analysis.SPSS was used for multivariate analysis.Results A total of 135 MSM were recruited within 10 weeks.75%were with senior high school or higher;the awareness rates on HIV/AIDS were 91.3%;53.6%reported condom use consistently during anal intercourse in the last 6 months.The crude prevalenc rates of HIV, HCV and syphilis were 13.3%(18/135),1.5(2/135) and 8.1%(11/135) respectively.The adjusted prevalence rates of HIV,HCV and syphilis were 15.1%(95%C/:7.3%- 25.6%),3.0%(95%Ci:0 - 4.2%) and 8.9%(95%CI:3.3%-17.5%) respectively.Multiple logistic regression indicated that,those who reported inconsistent condom use during anal sex in the last 6 months(AOR=10.19,95%CI:2.14 -48.67),and those who didn’t have HTV test(AOR=15.09,95%CI:1.88 - 120.98) in the last year were more likely to be HIV sero-positive.Conclusions A high HIV infection rate was observed among MSM in Zhongshan with high risk behaviors.Targeted interventions are necessary to prevent HIV spreading in MSM.更多还原