【作者】 韩焕美； 郑新华； 陈晞； 何桂华； 张爱霞； 肖守军；

【Author】 HAN Huan-mei 1*,ZHENG Xin-hua 1,CHEN Xi 1,HE Gui-hua 1,ZHANG Ai-xia 1,XIAO Shou-jun 2 (1.Jinan Entry-Exit Inspection and Quarantine Bureau,Jinan 250014,China;2.School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210093,China)

【机构】 济南出入境检验检疫局； 南京大学化学化工学院；

【摘要】 本文合成了5,5-二乙烯基-2,2-联吡啶,并成功将其嫁接到多孔硅表面形成有机单分子膜。比较了分别经5,5-二乙烯基-2,2-联吡啶、十一烯酸单分子层修饰以及未修饰的多孔硅在水溶液中的耐用性。在5,5-二乙烯基-2,2-联吡啶单分子膜的基础上共价偶联了十一烯酸,并最终制备蛋白质微阵列。检测结果表明,虽然联吡啶单分子层对生物芯片固定蛋白质效率有稍微影响,但其在减缓多孔硅氧化和微孔结构退化方面有着显著效果。更多还原

【Abstract】 5,5’-Divinyl-2,2’-bipyridine can be grafted on porous silicon surface by microwave irradiation.And porous silicon samples modified with 5,5’-divinyl-2,2’-bipyridine,modified with undec-10-enoic acid and without modification were destroyed with aqueous solution,respectively.The results indicated that grafting 5,5’-divinyl-2,2’-bipyridine is a straightforward and impactful method to protect porous silicon from oxidation and degradation.And then,we post-grafted undec-10-enoic acid after grafting 5,5’-divinyl-2,2’-bipyridine.The two organic molecules crown porous silicon are confirmed to be a real and more mercantile biochip.The results also confirm the advantage of 5,5’-divinyl-2,2’-bipyridine monolayer preventing porous silicon from oxidation and degradation and a little influence leading porous silicon to be a real biochip.更多还原