【作者】 周瑞华； 何晶伟； 宁洪珍； 唐咏梅； 刘辉； 韩青芳；

【Author】 ZHOU rui-hua,HE jing-wei,Han jing-fang,et al.North China Coal Medical University (Tangshan 063000,China)

【机构】 华北煤炭医学院预防医学系国家煤矿职业卫生与安全重点实验室；

【摘要】 目的 2型糖尿病患者多并发高脂血症。而伴有高脂血症的糖尿病患者心脑血管疾病的发病率明显增高。本文旨在探讨分析糖尿病患者高脂血症的主要影响因素,为2型糖尿病合并高脂血症的预防和治疗提供参考资料。方法 2009年3月至6月间,对唐山某医院内分泌科住院的110例2型糖尿病患者进行血脂的测定并进行膳食因素的问卷调查。调查内容包括一般饮食习惯和24小时膳食回顾。结果 1.按体质量指数将研究对象分成<24.0kg/m~2和≥24.0kg/m~2两组,前者CHOL的平均水平为5.45±1.20 mmol/l,低于后者的平均水平(5.57±1.00 mmol/1),差异有统计学意义(P<0.05)。前者平均TG、LDLC分别为1.68±1.02 mmol/1和1.63±0.41mmol/l,明显低于后者的(1.99±1.20)mmol/1和(1.43±0.34)mmol/l,差异均有统计学意义(P<0.05)。进一步对体质量指数与血脂进行相关性分析,结果显示,体质量指数与CHOL、TG、LDLC分别成正相关(r=0.51,0.36,0.42,P<0.05),与HDLC无相关性(P>0.05)。2.按照各种营养素摄入量或食物摄入频率将研究对象分层,经统计分析,结果显示:膳食纤维、豆类及豆制品、鱼虾类、畜、禽肉类以及吸烟、饮酒的摄入对血脂均有影响,(P<0.05)。3.进一步将每日畜、禽肉类摄入量与血脂的四个指标进行相关性分析,结果表明每日畜、禽肉类摄入量与CHOL、HDLC、LDLC均成正相关(r=0.69,0.31,0.81,P<0.05),与TG无相关(P>0.05)。结论膳食纤维、豆类及豆制品、鱼虾类、畜禽肉类摄入及体质量指数是2型糖尿病人血脂水平的主要影响因素。更多还原

【Abstract】 Objective:To investigate and analysis the main influences for blood lipids of patients with type 2 diabetes.Methods:110 patients with type 2 diabetes were selected.Every person in study had a detection of lipids and completed a questionnaire.The content of the questionnaire includes general diet survey and a 24-hour diet.Results:(1) According to their BMI,110 patients were divided into 2 groups.The BMI≤24.0kg / m2 was in group A,while the others were in group B.The mean CHOL level of A group(5.45±1.20mmol/1) is lower than the group B(5.57±1.00 mmol/l)(P>0.05).The TG mean level of the group A(1.68±1.02 mmol/l) is lower than the group B(1.99±1.20 mmol/1)(P>0.05).The LDLC mean level of the group A(1.63±0.41 mmol/1)is lower than the group B(1.43±0.34)mmol/1(P>0.05).The results of the linear correlation analysis of Body Mass Index and lipids show that Body Mass Index with CHOL、LDLC and TG has a positive correlation(r=0.51,0.36,0.42,P<0.05) while no relationship with HDLC(P>0.05).(2) The objects in study were divided into different groups according to the amount and frequency of the nutrients intakes.The results show that dietary fiber,beans and soy products,fish and shrimp, smoking,drinking,Livestock and poultry meat and body mass index are all related to the lipid levels after t-test or Analysis of variance(P<0.05).(3) The results of the linear correlation of the everyday intake amount of Livestock and poultry meat and lipid levels show that the amount has a positive correlation with CHOL HDLC and LDLC(r=0.69,0.31,0.81,P<0.05 = while no relationship with TG(P>0.05).Conclusions:The factors of effecting the lipid levels of patients with type 2 diabetes include dietary fiber,beans and soy products,fish and shrimp,smoking,drinking, Livestock and poultry meat and body mass index.更多还原