【作者】 薛建军； 杨爱民； 邓惠兴； 冉宏德； 程虎；

【Author】 XUE Jian-jun,YANG Ai-min,DENG Hui-xing,RAN Hong-de,CHENG Hu (Department of Nuclear Medicine,the First Affiliated Hospital,Medical School of Xi’an Jiaotong University, Xi’an 710061,China;)

【机构】 西安交通大学医学院第一附属医院核医学科；

【摘要】 目的:制定⁹⁹Tc^m-DTPA测定肾小球滤过率（GFR）在不同年龄组中的正常参考范围,评价其在移植肾活体供体中的临床价值。方法:300例移植肾供体行肾动态显像,应用Gates法计算GFR,统计分析GFR正常参考范围及不同年龄组GFR正常参考范围,分析其与性别、年龄、身高体重指数的关系。结果:300例供肾者左肾、右肾及总肾的GFR为（49.25±10.34）ml/min、（49.27±9.69）ml/min及（98.52±19.03）ml/min;<50岁者的GFR显著高于≥50岁者,<50岁或≥50岁,各年龄组间GFR无显著性差异;logistic回归分析表明GFR仅于年龄相关。结论:⁹⁹Tc^m-DTPA肾动态显像测定GFR方法简便、可靠,可以反映分肾功能,评估尿路排泄情况,对筛选移植肾供体具有一定价值。更多还原

【Abstract】 Objective To determine the normal reference range of glomerular filtration rate（GFR） in different ages with ⁹⁹Tc^m-DTPA renal dynamic imaging on living kidney transplantation donor,and to evaluate the clinical value of GFR in living kidney transplantation.Methods ⁹⁹Tc^m -DTPA renal dynamic imaging was performed in 300 patients on living kidney transplantation donor.The image was processed according to Gates’ method to obtain GFR.The normal reference range of GFR was obtained in different ages and the relationship betwwen GFR and gender,age and body mass index was also analyzed.Results The left,right and total renal GFR of 300 living kidney transplantation donors were 49.25±10.34 ml/min、49.27±9.69 ml/min and 98.52±19.03ml/min,respectively.The GFR in the group of age<50 was higher significantly than that of age≥50（P<0.05）.There was no significant difference among the groups of age<50 and age≥50（P>0.05）.The study of logistic regression showed that the age was the only important impact factor on GFR.Conclusions GFR obtained by ⁹⁹Tc^m-DTPA is simple and reliable,which can be used to accurately assess the individual renal filterability and the urinary drainage function,This affords an useful method on screening the living relative kidney transplantation donor.更多还原