【作者】 苗蕾； 姚华； 孙玉萍； 木斯林·苏克尔拜； 史惠；

【Author】 MIAO Lei~1 YAO Hua~2 SUN Yu-ping~3 Musilin~4 Shi Hui~5 (Xinjiang Medical University,Urumqi;The First Teaching Hospital of Xinjiang Medical University, Urumqi;College of Fundamental,Xinjiang Medical University,Urumqi,830011; Xinjiang Altay Kazakh Medical Hospital,Altay,836500,China)

【机构】 新疆医科大学公共卫生学院；

【摘要】 探计HDL-C在新疆地区不同民族人群高尿酸血症发生中的异质性。调查三民族人群,血清检测血尿酸及血脂等相关生化指标维、汉族的HDL-C均为对照组高于高尿酸组,而哈族HDL-C为高尿酸组高于对照组,哈族血尿酸水平最低:相关性分析发现哈族尿酸与HDL-C呈负相关(P<0.05)。HDL-C是心血管相关疾病较为公认的保护因子,在哈萨克族人群中血尿酸水平较低时,随尿酸的升高HDL-C也升高,当血尿酸水平高过一定标准(如高于本次分级SUA-4)时才对心血管疾病产生负面影响,提示应关注哈萨克族的特殊遗传性,为高尿酸血症的防治提供新思路。更多还原

【Abstract】 To analysis the heterogeneity of HDL-C in hyperuricemia on Uygur、Han and Kazak ethnic in Xinjiang. A total of 2396 cases were Surveyed.The HDL-C levels were significantly decreased in hyperuricemia group compared with control group on Han and Uygur but Kazak.The level of Kazak SUA was the lowest.The SUA was positive correlated with HDL-C on Han and Uygur but Kazak(P < 0.05 ).HDL-C is a recognized protective factor for cardiovascular disease.When the SUA is lower in the Kazak group,HDL-C will be increased with SUA;when SUA level is higher than a certain standard(such as the SUA -4) that it will have a negative impact on cardiovascular disease.更多还原