【作者】 冯连贵； 丁贤彬； 卢戎戎； 欧阳琳； 郑建琼； 徐静； 韩梅； 郭晓嘉； 杨明芳； 徐世明；

【Author】 FENG Liangui 1,DING Xianbin2,LU Rongrong,et al..(Chongqing Center for disease prevention and control,Chongqing 400042 )

【机构】 重庆市疾病预防控制中心； 重庆市疾病预防控制中心性艾所； 重庆市疾病预防控制中心微生物安全检测所；

【摘要】 目的了解MSM人群HIV抗体阳转率及其影响因素,为评估MSM人群艾滋病防治效果与开展有针对性的防治工作提供依据。方法对招募自愿参加随访研究的HIV与梅毒均阴性的MSM于6个月后再次进行问卷调查与采集血样检测HIV与梅毒,以HIV抗体阳转率为应变量,人口学特征、性行为情况等为自变量进行Logistic回归分析鉴别HIV抗体阳转率的影响因素。结果参加随访214例,平均年龄(25.6±6.3)岁,88.3%的人最近六个月与男性有肛交史,最近六个月平均性伴数为2个,最近一次与男性发生肛交时安全套使用率为76.2%,最近六个月发生保护性肛交的比例为52.4%。HIV发病率为12.5/100人年(9.1-15.7/100人年),梅毒的发病率为17.8/100人年(13.1-23.5/100人年)。多因素回归分析提示文化程度(OR=0.27,95%CI:0.13-0.59)、梅毒感染(OR=9.23,95%CI:2.42-35.18)是HIV抗体阳转率的独立影响因素。结论重庆市MSM人群HIV抗体阳转率高,安全套使用率低,防治形势严峻。更多还原

【Abstract】 Objective To understand HIV seroconversion rate and its associated factors among men who have sex with men is to provide the evidence for evaluating the effect and developing the comprehensive strategy for AIDS prevention and control among men who have sex with men.Methods MSM with HIV and Syphilis negative recruited were interviewed with the structured questionnaire and taken blood sample tested HIV and Syphilis antibody after six months.HIV seroconversion rate and its influence factors were analyzed by multivariable logistic regression.Results A total of 214 MSM participated in the follow-up study. The average age was(25.6±6.3) years old.88.3%of them had anal sex with men.The number of partners was 2(median).The rate of condom use in the last time and in recent six months was 76.2%and 52.4%respectively.HIV seroconversion rate was 12.4/100 person-year(9.l-15.7/100person-year).Syphilis incidence was 17.8/100 person-year(13. 1-23.5/100 person-years).The result of multivariate analysis indicated that education level (OR=0.27,95%CI:0.13-0.59) and Syphilis positive(OR=9.23,95%CI:2.42-35.18) were independent factors of HIV seroconversion rate.Conclusion HIV seroconversion rate was high and the rate of condom use was low among men who have sex with men.AIDS epidemic among men who have sex with men was serious.更多还原