【作者】 宋文丰； 钟晓妮； 罗蓉； 王永宏； 李永强； 田考聪；

【Author】 SONG Wen-feng,ZHONG Xiao-ni,LUO Rong,WANG Yong-hong,LI Yong-qiang,TIAN Kao-cong.Department of Biostatistics,Public Health school,Chongqing medical university,Chongqing 400016,China

【机构】 重庆医科大学公共卫生学院流行病与卫生统计教研室； 重庆医科大学第一附属医院体检中心；

【摘要】 目的使用腰围身高比(WHR)来探测重庆市成年人正常体重中心肥胖和心血管疾病危险因素。方法在重庆市"一小时经济圈"内采用整群抽样的方法抽取了20 000名18～59岁的在职正常成年人,测量其身高、腰围(WC)、体重,计算体质指数(BMI)和WHR,检测血压、血脂和血糖水平。分析正常体重[18.5≤BMI(kg/m2)<24]非中心肥胖组(WHR<0.5)与中心肥胖组(WHR≥0.5)相关指标的差异,用logistic回归分析中心肥胖和心血管各危险因素之间的关系。结果在11 612名正常体重者中,1801(15.51%)名为正常体重中心肥胖。正常体重非中心肥胖组与中心肥胖组WC水平分别为(73.71±5.91、(84.47±4.58)cm(F=328.74,P<0.01);舒张压水平分别为(72.85±10.30)、(78.22±11.90)mmHg(1 mm Hg=0.133 kPa,F=23.62,P<0.01);甘油三酯分别为(1.22±0.95)、(1.97±1.91)mmol/L(F=114.70,P<0.01);总胆固醇含量分别为(4.66±0.84)、(5.04±0.92)mmol/L(F=13.10,P<0.01);高密度脂蛋白分别为(1.41±0.31)、(1.25±0.29)mmol/L(F=29.44,P<0.01);低密度脂蛋白含量分别为(2.65±0.74)、(3.03±0.77)mmol/L(F=9.98,P<0.01);血糖水平分别为(4.94±0.82)、(5.25±1.37)mmol/L(F=47.21,P<0.01)。logistic回归分析结果显示,正常体重中心肥胖组的收缩压、舒张压、甘油三酯、高密度脂蛋白、低密度脂蛋白和血糖的OR值(95%CI值)分别是1.28(1.02～1.60)、1.49(1.20～1.84)、2.24(1.92～2.60)、1.77(1.53～2.05)、1.58(1.15～2.16)和1.31(1.06～1.63)。结论 WHR能够较有效的分析正常体重中心肥胖和各心血管疾病危险因素,高收缩压、高舒张压、高甘油三酯、低高密度脂蛋白、高低密度脂蛋白和血糖升高是正常体重中心肥胖者的心血管疾病危险因素。更多还原

【Abstract】 Objective To detect central obesity and related adverse cardiovascular disease risk factors by waist-to-height ratio(WHR) among normal weight adults in Chongqing area.Methods A total of 20 000 participants aged 18?59 from one hour economic cycle of Chongqing area were selected by group sampling method.We measured the height,waist circumference(WC),body weight,blood pressure,blood lipid and blood sugar.Body Mass Index(BMI) and WHR were computed.We analyzed the differences of the correlated indexes between non-central obesity group(WHR<0.5) and central obesity group(WHR ≥ 0.5) of those had normal weight(18.5≤BM(Ikg/m2)<24).And we used logistic regression method to analyze the relation between central obesity and related adverse cardiovascular risk factors.Results Among 11612 normal weight subjects,1801(15.51%) participants were normal weight central obesity.Of non-central obesity group and central obesity group,the levels of waist WC were(73.71 ± 5.91) and(84.47 ± 4.58)cm(F=328.74,P<0.01);diastolic blood pressure levels were(72.85±10.30) and(78.22± 11.90)mmHg(1 mm Hg=0.133 kPa,F=23.62,P<0.01);triglyceride levels were(1.22±0.95)、(1.97±1.91)mmol/L(F=114.70,P<0.01);total cholesterol levels were(4.66±0.84) and(5.04±0.92)mmol/L(F=13.10,P<0.01);high density lipoprotein levels were(1.41±0.31)、(1.25±0.29)mmol/L(F=29.44,P<0.01);low density lipoprotein levels were(2.65 ± 0.74) and(3.03 ± 0.77)mmol/L (F=9.98,P<0.01);glycemia levels were(4.94±0.82) and(5.25±1.37)mmol/L(F=47.21,P<0.01).The results of the logistic regression analysis showed the OR values of systolic blood pressure,diastolic blood pressure,triglyceride,high density lipoprotein,low density lipoprotein and blood glucose in central obesity normal weight group were 1.28(1.02～1.60),1.49(1.20～1.84),2.24(1.92～2.60),1.77(1.53～2.05),1.58(1.15～2.16)and 1.31(1.06～1.63).Conclusion WHR can effectively reflect the normal weight central obesity and the risk factors of cardiovascular disease;high blood pressure levels、high triglyceride level,low high density lipoprotein level,high low density lipoprotein level were related adverse cardiovascular disease risk factors among normal weight adults with central obesity.更多还原