【作者】 李心术； 廖文芳； 谢军； 罗飞； 陈静； 周倩如；

【Author】 LI Xin-shu,LIAO Wen-fang,,XIE Jun,LUO Fei,CHEN Jing,ZHOU Qian-ru.Department of Endemic and Parasitic Diseases,Chongqing Municipal Center for Disease Control and Prevention,Chongqing 400042,China.

【机构】 重庆市疾病预防控制中心；

【摘要】 目的了解重庆市碘缺乏病高危地区重点人群碘营养状况,有针对性地提出防治对策,杜绝新发地方性克汀病(简称地克病)的发生。方法2007年4-5月,在重庆市城口、巫溪县的6个乡镇,搜索所有的1997年1月1日以后出生的疑似地克病儿童;在每个乡分别选择8～10岁儿童200人,进行甲状腺检查、智商测定和采集尿样测定尿碘;在每乡抽取育龄妇女(孕妇和哺乳期)40人进行家庭食用盐碘测定和调查居民碘盐覆盖率。儿童甲状腺检查采用诊法和B超法,智商测定采用《中国瑞文联合型测验》农村版,尿碘测定采用酸消化砷铈分光光度法,盐碘测定采用直接滴定法。结果城口、巫溪县乡镇医院报告疑似地克病6例,排除5例,另外1例为外地出生;8～10岁儿童甲状腺触诊法肿大率为9.58%(92/960),B超法肿大率为8.89%(65/731);儿童平均智商(IQ)为103.32;尿碘中位数为319.15μg/L,妇女尿碘中位数为248.42μg/L;居民碘盐覆盖率为98.82%(336/340)。结论重庆市城口、巫溪县儿童碘营养状况良好,未发现当地出生的新发地克病患儿;8～10岁儿童甲状腺肿大率和尿碘中位数,妇女尿碘中位数和居民碘盐覆盖率达到基本消除碘缺乏病标准。更多还原

【Abstract】 Objective To investigate the iodine nutrition of emphatic crowns of the high risk areas of iodine deficiency disorders in Chongqing,so as to provide scientific evidence for establishing prevention and remedial measures.Methods 6 towns were select in Chengkou County and Wuxi County to found suspected dementia Patients birthed after 1st Jan,1997. 200 children aged 8～10 years were investigated in every town.The thyroid volume, intelligence quotient(IQ) and urinary iodine of the children were examined.40 women (pregnant and nursing women) were investigated in every town.The iodine content of their salt was measured.The thyroid volume was examined by B-ultrasound and palpation.IQ was measured by Raven’s test and combined Raven’s Test in China(CRT-RC2).The acid digest arsenic-cerium contacting method was determined urinary iodine,and iodine of in salt was detected using direst titration method.Result 6 suspected dementia Patients were found in the local town hospital.5 cases were excluded.There was 1 case birthed in other place. The rate of goiter by B-ultrasound and palpation was respectively 9.58%and 8.89%.The median of urinary iodine of children and women was respectively 319.15μg/L and 248.42μg/L.The mean of IQ of the children was 103.32.The coverage rate of resident iodine salt was 98.82%.Conclusions The iodine nutrition of children was good and there was no newly occurred cretinism in Chengkou County and Wuxi County.Goiter rate and median of urinary iodine aged 8-10 years,median of urinary iodine of women,coverage rate of resident iodine salt has meet the standard set for basically elimination iodine deficiency disorders.更多还原