【作者】 李昂；

【导师】 张扬；

【作者基本信息】 大连理工大学 ， 电子信息， 2024， 硕士

【摘要】 表面等离子体共振(Surface Plasmon Resonance,SPR)是一种通过分析表面等离子体波共振效应的光谱特征进行界面结构分析的光学检测方法,在药物筛选、环境监测等领域具有广泛应用。近年来,关于棱镜SPR传感系统的研究从不同的研究角度出发,着力优化系统架构,提升系统的灵敏度、分辨率,拓展系统探测类型,提高检测能力等,为棱镜SPR传感系统的发展提供更加全面的理论和技术支撑。然而,限制棱镜SPR传感系统应用与推广的关键是系统成本、检测能力,而特殊要求的SPR传感系统多数需要定制,这在一定程度上也增加了系统开发和应用的成本。因此,小型化、低成本的SPR检测系统开发将有助于推动SPR传感技术和系统的应用与推广。本文围绕小型化SPR传感系统的设计与开发展开研究,对SPR传感系统实时信号采集与处理中的关键问题进行了深入的研究,并提出了一种基于ZYNQ平台的SPR光谱信号解调系统设计方案,该方案将SPR传感系统的解调单元与ZYNQ平台下的嵌入式Linux开发相结合,实现了以基于ZYNQ平台的高速数据采集和处理技术替代传统SPR传感系统光谱分析解调方案,并在实验上验证了设计方案的可行性。论文的主要工作如下:1.基于ZYNQ平台设计了SPR光谱解调系统的硬件部分,包括解调系统的电路板设计和Linux环境搭建。所设计的解调系统满足了SPR传感系统低成本和小型化的要求,同时兼顾了系统灵活配置和定制化的需求,有利于SPR传感系统适应不同的应用场景和用户需求,也为后续二次开发和升级提供了便利。2.在所设计的解调系统硬件环境中,设计了基于Qt框架的嵌入式人机交互界面,并实现了SPR光谱信息的实时采集、处理、显示、运算和存储等功能;便携式的数据处理能够简化SPR传感系统现场检测的操作步骤,提升检测效率。3.以Kretschmann棱镜耦合方式构建SPR传感系统光学架构,利用透射光栅与线阵CCD相结合的空间光强探测方案实现SPR传感系统的光谱检测,采用光路仿真对光学系统配置进行设计优化,组装空间强度调制SPR传感系统,对其性能进行分析验证。在实验上,对所设计的小型化SPR传感系统的性能进行了测试分析,SPR传感系统的平均折射率灵敏度为35810pixel/RIU,系统的测量误差小于0.045%RIU。实验结果表明,本文设计的基于ZYNQ平台的SPR光谱信号解调系统具有良好的稳定性和实时性,能够满足实时检测和现场检测等实际测量需求。更多还原

【Abstract】 Surface Plasmon Resonance(SPR)is an optical detection method to analyze the interface structure by analyzing the spectral characteristics of the surface plasmon wave resonance effect,which has been widely used in drug screening,environmental monitoring and other fields.In recent years,the research on prism SPR sensing system has focused on optimizing the system architecture,improving the sensitivity and resolution of the system,expanding the detection types of the system,improving the detection capability and so on,from different research perspectives,so as to provide more comprehensive theoretical and technical support for the development of prism SPR sensing system.However,the key to limit the application and promotion of prism SPR sensing system is the system cost and detection capability,and most SPR sensing systems with special requirements need to be customized,which also increases the cost of system development and application to a certain extent.Therefore,the development of miniaturized and low-cost SPR detection system will help promote the application and popularization of SPR sensing technology and system.This paper focuses on the design and development of miniaturized SPR sensing system,conducts in-depth research on the key issues in real-time signal acquisition and processing of SPR sensing system,and proposes a design scheme of SPR spectral signal demodulation system based on ZYNQ platform.This scheme combines the demodulation unit of SPR sensing system with the development of embedded Linux under ZYNQ platform,and realizes the spectral analysis demodulation scheme of traditional SPR sensing system with high-speed data acquisition and processing technology based on ZYNQ platform.The feasibility of the design scheme is verified by experiments.The main work of this paper is as follows:1.Designed the hardware part of the SPR spectral demodulation system based on ZYNQ platform,including the circuit board design of the demodulation system and the establishment of Linux environment.The designed demodulation system meets the requirements of low cost and miniaturization of SPR sensing system,and also takes into account the needs of flexible configuration and customization of the system,which is conducive to adapting the SPR sensing system to different application scenarios and user needs,and also provides convenience for subsequent secondary development and upgrade.2.In the hardware environment of the designed demodulation system,the embedded human-computer interface based on Qt framework is designed,and the functions of real-time acquisition,processing,display,calculation and storage of SPR spectral information are realized.Portable data processing simplifies the field inspection of the SPR sensing system and improves the inspection efficiency.3.Construct the optical architecture of the SPR sensing system by coupling with Kretschmann prism,realize the spectral detection of the SPR sensing system by using the spatial light intensity detection scheme combining transmission grating and linear array CCD,design and optimize the optical system configuration by using optical path simulation,and assemble the spatial intensity modulation SPR sensing system.Its performance is analyzed and verified.In the experiment,the performance of the designed miniaturized SPR sensor system is tested and analyzed.The average refractive index sensitivity of the SPR sensor system is35810pixel/RIU,and the measurement error of the system is less than 0.045%RIU.The experimental results show that the SPR spectral signal demodulation system based on ZYNQ platform has good stability and real-time performance,and can meet the actual measurement requirements such as real-time detection and field detection.更多还原