【作者】 张帅；

【导师】 万洪丹；

【作者基本信息】 南京邮电大学 ， 电子信息硕士（专业学位）， 2023， 硕士

【摘要】 具有极高品质因子(Quality factor,Q)、极小模式体积和多种结构、材质的回音壁模式(Whispering gallery mode,WGM)光学微腔在高灵敏传感检测、光电子器件、非线性光学和基础物理等领域具有广阔的研究和应用前景。本论文的研究课题主要包含微腔的制备加工及其相关研究,包含模场调控、温度和生化等传感。本论文的研究内容主要如下:1、基于不同类型的微腔特性与传感性能分析。首先介绍了锥形光纤和不同结构微腔的制备及其封装方法。其次,为了研究微腔的传输特性,介绍了两种微腔耦合探测系统。最后,分别研究了不同微腔的Q值特性、传感性能和模场调控的特性。1)Q值特性:空心微瓶腔的Q值约为10~6～10~7,实心微瓶腔的Q值约为10~7～10~8,微柱腔和耦合型微腔的Q值约10~4。2)传感性能:空心微瓶腔的温度灵敏度为10.43 pm/℃,体折射率灵敏度为6.31 nm/RIU;实心微瓶腔的温度灵敏度为13.71 pm/℃。3)模场调控特性:微柱腔实现了法诺共振的完整周期的调控,耦合型微柱腔实现了模式分裂及分裂间距可控的调控。2、提出了一种基于DNA纳米结构探针(DNA nanostructured probes,DNPs)功能化的高Q值光学微腔的无标记DNA生物传感器。利用DNPs作为探针,功能化改善传感器界面,减少探针的堆叠和缠绕效应,提高探针效率。DNPs合成效率达95%以上,通过荧光检测,DNPs与表面功能化的微腔和目标ss DNA之间的结合效率分别为92.8%和94.11%。提出的生物传感器实现了260 a M的超低的检测极限、约40 min的检测时间和单碱基错配识别。3、提出一种基于氧化石墨烯(Graphene oxide,GO)功能化的高Q值光学微腔的无标记DNA生物传感器。GO的沉积有助于提高光与物质的相互作用。硅烷化处理方法实现了GO在微腔内表面较为均匀的沉积。通过活化GO表面的羧基,实现了DNPs与GO的连接。提出的生物传感器实现了79 a M的超低检测极限、约48 min的检测时间和单碱基错配识别,并且实现了-1.522 pm/log f M的DNA检测灵敏度。4、提出一种基于长管道式的高Q值光学微腔的超高灵敏度的流速传感器,并实现了微压状态下微腔回音壁模共振光场对流体直接检测以相关应用。调控和优化拉锥机参数制备了高Q值长管道光学微腔,并通过仿真对该微腔的流速、光场进行详细分析。在不借助其他效应(表面等离子共振、法诺等),增强了微腔光场与腔内流体的互作用感知能力。提出的传感器获得了流速灵敏度为0.27 pm/(μL/min)、分辨率为1.43μL/min的高性能流速传感。基于高灵敏流速传感实现了微腔体折射率灵敏度增强,管内溶液性质和管内状态情况检测的应用。更多还原

【Abstract】 Whispering gallery mode(WGM)optical microcavity with extremely high-quality factor(Q)value,extremely small mode volume and various structures or materials has broad research and application prospects in the fields of highly sensitive sensing detection,optoelectronic devices,nonlinear optics and basic physics.The research topic of this paper mainly includes the preparation,processing,and related research of microcavities,with research fields including mode field regulation,temperature,and biochemical sensing.The main research contents of this paper are as follows:1.Analysis of the characteristics and sensing performance of different types of microcavities.Firstly,the preparation and packaging methods of tapered fiber and microcavities with different structures were introduced.Secondly,two types of microcavity coupling detection systems were presented to study the transmission characteristics of microcavities.Finally,the Q-value,sensing performance,and mode field regulation characteristics of different microcavities were investigated,respectively.1)Q-value characteristics:the Q-value of hollow-core microbottle cavity is about 10~6～10~7,the Q-value of solid-core microbottle cavity is about 10~7～10~8,and the Q-value of microcylindrical cavity and coupled microcylindrical cavity is about 10~4.2)Sensing performance:the temperature sensitivity of the hollow-core microbottle cavity is 10.43 pm/℃,and the volume refractive index sensitivity is 6.31 nm/RIU,the temperature sensitivity of the solid-core microbottle cavity is 13.71 pm/℃.3)Mode field regulation characteristics:the microcylindrical cavity achieves the regulation of the complete period of the Fano resonance,while the coupled microcylindrical cavity achieves the regulation of mode splitting and controllable splitting spacing.2.A label-free DNA biosensor based on high Q-value optical microcavities functionalized by DNA nanostructured probes(DNPs)was proposed.By using DNPs,the surface functionalization quality of the sensor interface is improved,and the stacking and wrapping effects of the probes are reduced.The synthesis efficiency of DNPs is over 95%.Through fluorescence detection,the binding efficiency between DNPs and surface functionalized microcavities and target single-stranded DNA(ss DNA)is 92.8%and 94.11%,respectively.The proposed biosensor achieves an ultra-low detection limit of 260 a M,a detection time of about 40 min and single base mismatch recognition.3.A label-free DNA biosensor based on high Q-value optical microcavity functionalized by graphene oxide(GO)was proposed.The deposition of GO helps to enhance the interaction between light and matter.Through silanization treatment,GO was deposited uniformly on the surface of the microcavity.By activating the carboxyl groups on the surface of GO,effective connection between DNPs and GO is achieved.The proposed biosensor achieves an ultra-low detection limit of 79 a M,a detection time of about 48 min and single base mismatch recognition,and achieves DNA detection sensitivity of-1.522 pm/log f M.4.An ultra-high sensitivity flow rate detection based on a long pipeline-type high Q-value optical microcavity was proposed,and achieve direct detection of fluid based on microcavity and related applications under micro pressure state.A high Q-value long pipeline optical microcavity was prepared by adjusting the parameters of the cone-pulling machine,and the flow rate and light field of the microcavity were analyzed in detail through simulation.Without the help of other effects(Surface plasmon resonance,Fano,etc.),the sensing ability of the interaction between the microcavity light field and the cavity fluid is enhanced.The proposed sensor achieved high-performance flow rate sensing with a flow rate sensitivity of 0.27 pm/(μL/min)and a resolution of 1.43μL/min.Based on highly sensitive flow rate sensing,the application of enhancing the refractive index sensitivity of microcavity,detecting the properties of solution in the tube and the state inside the tube has been achieved.更多还原