【作者】 张宏宇；

【导师】 张宇曦；

【作者基本信息】 中国医科大学 ， 外科学（专业学位）， 2022， 硕士

【摘要】 目的:研究勃起功能障碍(ED)在心血管内科男性冠心病(CHD)住院患者中的发生情况,探讨其相关因素与ED发生的关系。研究方法:选择2020年8月至2021年11月于中国医科大学附属第一医院心血管内科病房住院的全部男性冠心病患者。对符合标准的研究对象(共150例)的数据进行统计分析,探讨ED在心血管内科男性CHD住院患者中的患病率。将研究对象依据是否患有勃起功能障碍分为两组:ED组(98例)和非ED组(52例)。探讨其相关因素与ED发生的关系时,采用多因素Logistic回归分析进行统计学分析。结果:1、ED在本中心心血管内科男性CHD住院患者中的患病率为65.33%,进一步分析发现,发生ED的时间平均早于CHD 4.58±0.32年。2、对比ED组与非ED组,两组在体重指数(BMI)、高血压、糖尿病、吸烟史和饮酒史方面均具有统计学差异(P<0.05)。进行多因素Logistic回归分析,调整混杂因素影响后,发现BMI、高血压、糖尿病、吸烟和饮酒的比值比(OR值)分别为1.714(95%CI1.075-2.733,P<0.05)、4.778(95%CI 1.048-21.781,P<0.05)、4.229(95%CI1.376-13.002,P<0.05)、2.401(95%CI 1.127-5.117,P<0.05)和3.102(95%CI1.102-8.731,P<0.05)。BMI、高血压、糖尿病、吸烟史和饮酒史均为ED的危险因素。结论:1、本中心心血管内科男性CHD住院患者中ED的患病率为65.33%。2、发生ED的时间平均早于CHD 4.58±0.32年,提示我们ED可能作为CHD的一种早期预测信号,为未来CHD事件的发生提供早期预防指导作用。3、BMI、高血压、糖尿病、吸烟史和饮酒史均是ED的危险因素。更多还原

【Abstract】 Objective: To investigate the incidence of erectile dysfunction(ED)in hospitalized male patients with coronary heart disease(CHD)in the department of cardiology,and to explore the relationship between ED and its related factors.Methods: All male patients with coronary heart disease admitted to the Department of Cardiovascular Medicine,the First Affiliated Hospital of China Medical University from August 2020 to November 2021 were selected.To investigate the prevalence of ED in male inpatients with CHD in the Department of Cardiovascular medicine by statistical analysis of data from 150 subjects who met the criteria.Subjects were divided into two groups based on erectile dysfunction: the ED group(98 cases)and the non-ED group(52 cases).Multivariate Logistic regression analysis was used to analyze the relationship between the related factors and the occurrence of ED.Results: 1.The prevalence of ED in male hospitalized CHD patients in the department of Cardiovascular Medicine of our center was 65.33%.Further analysis showed that the onset of ED was 4.58±0.32 years earlier than CHD on average.2.There were statistically significant differences in body mass index(BMI),hypertension,diabetes,smoking history and drinking history between the ED group and the non-ED group(P<0.05).After adjusting the influence of confounding factors,The odds ratios(OR)of BMI,hypertension,diabetes,smoking,and alcohol consumption were 1.714(95%CI1.075-2.733,P < 0.05),4.778(95%CI 1.048-21.781,P < 0.05),4.229(95%CI1.376-13.002,P < 0.05),2.401(95%CI 1.127-5.117,P < 0.05)and 3.102(95%CI1.102-8.731,P < 0.05).BMI,hypertension,diabetes mellitus,smoking history and drinking history are risk factors for ED.Conclusion: 1.The prevalence of ED among male CHD inpatients in the department of Cardiovascular Medicine of our center was 65.33%.2.The onset time of ED was4.58±0.32 years earlier than that of CHD,suggesting that ED may serve as an early predictive signal of CHD and provide early prevention guidance for the occurrence of CHD events in the future.3.BMI,hypertension,diabetes mellitus,smoking history and drinking history were all risk factors for ED.更多还原