【作者】 陈朋刚；

【导师】 杨鸣琦；

【作者基本信息】 西北农林科技大学 ， 兽医硕士（专业学位）， 2018， 硕士

【摘要】 在规模化猪场中,繁殖障碍性病毒病是较为重要、危害较严重的一类疾病。繁殖障碍性病毒病多发是严重影响养猪业健康发展的最主要原因。通过采取疫苗免疫接种是防控该类疾病有效措施。对免疫猪场定期进行抗体检测,有助于了解猪群抗体水平,确定合理的免疫接种时间,为猪场制定综合防控措施提供重要依据。为了解延安市主要猪繁殖障碍性疾病免疫情况,本论文对采自该市七个区县猪场的2363份血清样品进行抗体检测,分析猪瘟、猪繁殖与呼吸综合征、猪圆环病毒病、猪伪狂犬病这四种疫病免疫情况。结果显示:(1)七个区县猪场仔猪的猪瘟病毒血清抗体阳性率平均水平为78.94%,母猪的猪瘟病毒血清抗体阳性率平均水平为80.72%,并且全部达到国家规定合格率。(2)七个区县猪场仔猪的猪繁殖与呼吸综合症病毒血清抗体阳性率平均水平为76.85%,其中,子长、洛川和安塞猪场的仔猪猪繁殖与呼吸综合症病毒血清抗体阳性率未达到70%;母猪的猪繁殖与呼吸综合症病毒血清抗体阳性率平均水平为76.53%,洛川和安塞猪场的母猪猪繁殖与呼吸综合症病毒血清抗体阳性率未达到70%。(3)七个区县猪场仔猪的猪圆环病毒血清抗体阳性率平均水平为75.33%,其中,安塞猪场的仔猪圆环病毒血清抗体阳性率未达到70%;母猪圆环病毒血清抗体阳性率平均水平为78.40%,其中,子长猪场的母猪圆环病毒血清抗体阳性率未达到70%。(4)七个区县猪场仔猪的猪伪狂犬病毒gB血清抗体阳性率平均水平为79.74%,母猪的猪伪狂犬病毒gB血清抗体阳性率平均水平为81.37%,延长猪场的仔猪和母猪的猪伪狂犬病毒gB血清抗体阳性率均未达到70%。为初步探究实施综合防控措施后猪场四种繁殖障碍性病毒病的感染情况和猪群的生产性能情况,从延安市的七个区县分别选取一家基础母猪存栏量在150头以上的规模化猪场为研究对象:把关引种来源、制定科学的生物安全防范措施、加强猪场疫苗免疫、定期检测免疫情况、采取药物辅助控制继发性感染等一系列的综合防控措施,以抗原检测和抗体检测和猪群的生长性能作为评价依据,结果表明:猪瘟病毒、猪繁殖与呼吸综合症病毒、猪圆环病毒、猪伪狂犬病毒的抗原阳性率均明显降低,抗体保护率都有了显著的提升,猪群的生长性能也有了明显的提升,包括商品猪日均采食量、60日龄平均重和成活率、哺乳母猪产活仔数、仔猪断奶重以及成活率等。更多还原

【Abstract】 In the large-scale pig farm,the disease is more important and more serious.The most important reason for the healthy development of the pig industry is the proliferation of the disease.Vaccination is an effective way to prevent and control such diseases.Regular antibody detection for the immune pig farm,It is helpful to understand the antibody level of pigs,determine reasonable immunization time,and provide important basis for comprehensive prevention and control measures for pig farms.In order to understand the immune status of the main reproductive diseases of pigs in Yan ’An city,In this paper,2363 serum samples from the seven districts and counties of the city were tested for antibody(g B).To analyze the immune status of swine fever,porcine reproductive and respiratory syndrome,porcine circovirus disease and swine pseudorabies.Results show:Detected four swine virus antibodies in serum samples were collected from The seven counties form scale pig farms(2363 samples)in Yan’An city and the results show that:(1)The average levels of CSFV antibody positive rates of piglets and sows in seven counties were 78.94% and 80.72%,respectively,and all reached the national eligibility rate.(2)he average positive rates of PRRSV antibody in piglets and sows in seven counties were 76.85% and 76.53%,But the positive rate of serum antibodies PRRSV in piglets from Zichang,Luochuan and Ansai farms and sows form Luochuan and Ansai farms were not 70%.(3)The positive rates of PCV antibody in piglets and sows in seven counties were 75.33% and 78.40%,respectively。 Among them,the positive rate of serum antibody against PCV in piglets from Ansai pig farms and Zichang pig farms was not 70%.(4)The positive rates of PRV g B serum antibody in piglets and sows in seven counties were 79.74% and 81.37%,respectively,both the positive rate of PRV g B serum antibody of piglets and sows in Yanchang pig farm were not 70%.In order to explore the infection of four virus diseases and production performance of swine,integrated prevention and controled measures were initial taken in seven scale pig farms of Yan’An city.Including introduction,bio-security,vaccination,Immunoassay,medicines,based on antibody,pathogen detection and production results ultimately for final evaluation.The results showed that: CSFV,PRRSV,PRV,PCV were significantly reduced in antigen positive rate,there was a significant increase in antibody protection,the growth performance of the pigs also increased significantly,Including the average daily intake of commercial pigs.更多还原