【作者】 杨蕾；

【导师】 刘莉；

【作者基本信息】 黑龙江中医药大学 ， 中医学（七年制）（专业学位）， 2016， 硕士

【摘要】 目的：观察人参芍药散加减方治疗气虚血瘀型冠心病稳定性心绞痛患者的临床疗效。方法：采用随机对照分组法,将60例符合气虚血瘀型冠心病稳定性心绞痛诊断标准的患者分为治疗组和对照组,每组各30例。对照组给予冠心病心绞痛常规西药治疗,治疗组给予冠心病心绞痛常规西药和人参芍药散加减方治疗,疗程共28天。观察治疗前后患者的中医证候、心绞痛症状、心电图、硝酸甘油停减率、西雅图心绞痛量表的变化。结果：在中医证候改善方面,治疗组与对照组差异有统计学意义(p<0.05)。在心绞痛疗效方面,治疗组总有效率为83.33%,对照组总有效率为63.33%,差异具有统计学意义(p<0.05)。在心电图疗效方面,治疗组总有效率为63.33%,对照组总有效率为50.00%,差异无统计学意义(p>0.05)。在硝酸甘油停减率方面,治疗组停减率为90.00%,对照组为66.67%,差异具有统计学意义(p<0.05)。生活质量改善方面：西雅图心绞痛量表的五个项目进行比较,治疗组和对照组差异有统计学意义(p<0.05)。结论1.人参芍药散加减方可以改善气虚血瘀型冠心病稳定性心绞痛患者的中医证候,缓解心绞痛症状。2.人参芍药散加减方可以提高气虚血瘀型冠心病稳定性心绞痛患者的生活质量。更多还原

【Abstract】 Objective:To observe the clinical effect of modified Renshen Shaoyao Decoction on stable fatigue angina pectoris of coronary heart disease with qi deficiency and blood stasis.Methods:Select 60 cases of stable fatigue angina pectoris of coronary heart disease with qi deficiency and blood stasis. Divide them into control group and treatment group randomly,30 cases for each group. Treat the control group with conventional western medicine, while the treatment group combined with modified Renshen Shaoyao Decoction. The course of treatment was four weeks. Observe the change of traditional Chinese medicine syndrome, angina symptoms, electrocardiogram, the reducing and stopping rate of nitroglycerin, SAQ before and after treatment.Results:In terms of improving traditional Chinese medicine syndrome, the difference between the treatment group and the control group is statistically significant (p<0.05). On the aspect of angina curative effect:the treatment group is 83.33%, the control group is 63.33%, and it has significant difference (p<0.05). The treatment group and the control group have no dramatic difference in electrocardiogram (p>0.05), one is 63.33%, and the other is 50.00%. The two groups have statistical significance on reducing and stopping rate of nitroglycerin (p<0.05), the treatment group is 90.00%; the control group is 66.67%. In quality of life improvement:on the five aspects of SAQ, the treatment group and the control group have significant difference (p<0.05).Conclusion1. Modified Renshen shaoyao decoction for the treatment of stable fatigue stable angina with qi deficiency and blood stasis can improve traditional Chinese medicine syndrome, relieve angina symptoms.2. Modified Renshen shaoyao decoction for the treatment of stable fatigue stable angina with qi deficiency and blood stasis can improve patient quality of life.更多还原