【作者】 张欣；

【导师】 欧阳建东；

【作者基本信息】 山东中医药大学 ， 中西医结合临床（专业学位）， 2016， 硕士

【摘要】 目的:通过对益君康联合艾灸治疗腹泻型肠易激综合征的临床观察,分析其疗效及安全性,为采用此方案治疗腹泻型肠易激综合征提供资料,更好的指导临床治疗用药。方法:符合纳入标准的腹泻型肠易激综合征患者70例随机分成两组,治疗组和对照组各35例。对照组给予黄连素治疗;治疗组给予益君康加艾灸联合治疗。观察和记录两组患者治疗前后的症状积分变化、不良反应的类型、程度、发生率以及复发率。结果:66例完成治疗与复查。治疗组与对照组总有效率分别为87.88%和66.67%,显效率分别为60.61%和33.33%,两组患者总有效率和显效率比较均有统计学差异(P﹤0.05);在改善腹痛或腹部不适程度及频率、大便次数、大便性状、里急后重等症状积分方面治疗组明显优于对照组。两组治疗期间均未出现明显不良反应。停药4周后随访,治疗组共20例治愈及显效的患者中有4例(20.00%)复发或加重,对照组11例治愈及显效患者中有6例(54.55%)复发或加重,两组复发率比较,没有统计学差异(P﹥0.05)。结论:益君康联合艾灸在治疗腹泻型肠易激综合征方面疗效更好且不良反应少。更多还原

【Abstract】 Objective: Through the clinical observation on the treatment of diarrhea predominant irritable bowel syndrome by the combination of Yi Jun Kang and moxibustion, analysis its efficacy and safety, provide information for using this regimen in the treatment of diarrhea predominant irritable bowel syndrome(IBS) and better guide clinical medication.Methods:70 patients with diarrhea predominant irritable bowel syndrome were randomly divided into two groups, the treatment group and the control group, 35 cases in each group. The control group was given berberine;the treatment group was given the treatment of moxibustion combined with Yi Jun Kang and moxibustion. Observe and record the two groups of patients before and after the treatment of symptom score changes, the types of adverse reactions, degree, incidence rate and recurrence rate.Results:66 cases completed the treatment and review. The total efficiency of the treatment group and the control group were 87.88% and 66.67%, markedly effective rate were 60.61% and 33.33%, the total efficiency and remarkable efficiency of the two groups are statistically significant difference(P<0.05); in the improvement of abdominal pain or discomfort degree and frequency, stool frequency, stool, tenesmus symptom score in treatment group was better than control group. There were no obvious adverse reactions in the two groups during the treatment period. Withdrawal after 4 weeks follow-up, the treatment group has 20 patients were cured and markedly effective,and 4 cases(20.00%) recurrence or aggravation; the control group has 11 cases cured and markedly effective,and 6 cases(54.55%) recurrence or aggravate, recurrence rate comparison,there is no significant difference(P >0.05).Conclusion: It is better to treat diarrhea predominant irritable bowel syndrome with the combination of Yi Jun Kang and moxibustion,and there is less adverse reactions.更多还原