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自拟中药方剂在肝癌术后患者行肝动脉化疗栓塞治疗中的疗效研究

Efficacy Study of the Self-Made Chinese Medicine in Postoperative HCC Patients after TACE

【作者】 杨帆

【导师】 宋展;

【作者基本信息】 新乡医学院 , 中西医结合临床, 2015, 硕士

【摘要】 背景肝癌已经成为了我国癌症高发类型,肝癌外科术后给予肝动脉化疗栓塞治疗是非常普遍的综合治疗措施,但是介入术后常易出现栓塞综合征等不良后果,而中药以其自身特点,在肝癌介入术后的治疗中日益引起人们的重视。目的通过对比研究肝癌外科术后的两组病人(对照组和实验组)的生活功能状态,探讨自拟中药方剂在肝动脉化疗栓塞术后的疗效及患者获益程度,找寻相对有效能切实改善患者预后的治疗方法,从而对肝癌的临床治疗工作具有一定的借鉴意义。方法选取2010年1月-2013年12月间,我院收治的回顾性诊断为肝癌的患者96例,分别采用TACE和TACE+自拟中药方剂的方法治疗肝癌,对比分析两组患者的KPS评分,随访2014年12月31日止。结果实验组治疗后平均KPS评分为66分,较治疗前提升13分;而对照组治疗后仅较治疗前仅提升6分,达58分,两组治疗对比差异显著(P<0.05)。结论自拟中药方剂治疗短期可以明显提高患者KPS评分,改善患者TACE术后生活质量。

【Abstract】 ObjectiveLiver cancer has become high incident cancer in China. However in our country there is no standard and specific treatment uniform for liver cancer, the clinical effect of Chinese medicine was less. This article mainly aims at comparing the treatment methods of liver cancer(TFACE, TACE+ The self-made Chinese medicine treatment), hope it has guiding significance for clinical treatment work to liver cancer.MethodsSelected 96 patients with advanced hepatocellular carcinoma patients have been received from January of 2010 to December of 2013 in our hospital, adopted with TACE, TACE+The self-made Chinese medicine for liver cancer, compared with the KPS scores of the two groups, followed up until December 31 st,2014.ResultsThe KPS average scores of TACE+The self-made Chinese medicine is 66, compared with before treatment it improved 13; However TACE improved 6 scores and reach 58 scores after the treatment, it has significant difference with the two treatments (P<0.05)ConclusionThe traditional Chinese medicine treatment can obviously prolong the survival time of the patients, improved the KPS scores of the patients, TACE with The self-made Chinese medicine will get a better therapeutic effect.

【关键词】 肝癌介入治疗中药
【Key words】 Liver cancerInterventional therapyChinese Medicine
  • 【网络出版投稿人】 新乡医学院
  • 【网络出版年期】2017年 02期
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