【作者】 陈芳；

【导师】 黄莺；

【作者基本信息】 成都中医药大学 ， 中医外科学， 2015， 硕士

【摘要】 目的：从症状、皮损变化等方面观察白1号药浴方治疗进行期寻常型银屑病(血热证)的临床疗效,挖掘中医药外治法的特色及优势,更好地总结和学习导师的宝贵经验,客观地评价白疙1号药浴方治疗进行期寻常型银屑病(血热证)的疗效及作用优势,为银屑病患者寻求一种安全有效、标本兼顾的外用制剂及方法,为其在临床推广提供可参考依据。方法：收集符合中西医诊断标准及纳入标准的60例进行期寻常型银屑病(血热证)患者,采取随机对照试验方法,将研究患者按随机数字表法随机分为治疗组与对照组。两组均给予口服消银汤及外用蛇黄软膏为基础治疗,治疗组加用白疙1号药浴方药浴,对照组则用清水沐浴,3日一次,每次30分钟,每周2次,4周为1个疗程。观察治疗前后两组PASI评分、皮损面积、红斑、浸润、鳞屑多少、瘙痒程度等方面的变化,以及不良反应及病例复发情况,借助SPSS17.0统计软件对结果进行分析和疗效评定。结果：治疗组脱落0例,对照组脱落4例,最终获得有效病例56例作为研究对象,其中治疗组30例,对照组26例。两组患者经治疗后皮损均有不同程度改善,经统计学分析,两组治疗后PASI积分比较,P<0.05,有显著差异。治疗组总有效率为80.00%,对照组总有效率为69.23%,两组总体疗效比较,P<0.05,有统计学意义,说明两组间疗效具有显著性差异,表明治疗组疗效优于对照组。结论：本试验证实,白疤1号药浴方治疗进行期寻常型银屑病(血热证)临床有效,具有皮损消退较迅速,实用性强,患者依从性及耐受性较好,疗效佳,且无明显毒副作用等优点,为寻常型银屑病的治疗提供了一种简便廉验的方法,值得临床推广更多还原

【Abstract】 Objective:Observation of Baibi No.1 medicated bath treatment of psoriasis vulgarism (blood heat syndrome) clinical efficacy,symptoms,lesions from the changes. Mining the characteristics and advantages of external therapy of TCM (traditional Chinese medicine). And we can better summary and learning tutor’s valuable experience. Objective evaluation of psoriasis vulgaris in Baibi No.1 medicated bath therapy (blood heat syndrome) curative effect and advantage. To seek external preparation of both a safe and effective method for the sample and the patients with psoriasis, for its promotion in clinical reference.Method:To collect with traditional and Western medicine diagnostic criteria and inclusion criteria 60 cases of psoriasis vulgaris (blood heat syndrome) patients. To adopt the method of randomized controlled trials, we study the patients randomly divided into treatment group and control group. The two groups were given based therapy by oral Xiaoyin Decoction and external Snake yellow ointment. The treatment group was treated with Baibi No.l medicated bath, while the control group with water bath,3 days at a time,2 times a week, for 4 weeks. To observe the changes of two PASI score, lesion area, erythema, infiltration, itching degree scales much thickness and other aspects of the observed before and after treatment, and the adverse reactions and recurrence of cases, with the help of the results of the analysis and evaluation of curative effect of SPSS17.0 statistical software.Results:The treatment group fall off in 0 cases, and the control group 4 cases, eventually obtaining effective 56 cases as the research object, of which 30 cases of treatment group,26 cases in the control group. Two patients with skin lesions were improved in different degrees, through statistical analysis, the comparison of PASI score in two groups after treatment display P< 0.05, which indicates there are significant differences. The total effective rate of treatment group is 80%, and the control group is 69.23%.Compared to the overall efficacy of the two groups, it displays P< 0.05,which indicates the curative effect that has significant difference. Finally it indicates that the efficacy of the treatment group is better than the control group.Conclusion:The experiment proves that,Baibi No.1 medicated bath treatment of psoriasis vulgaris (blood heat syndrome) may provide a simple method for the treatment of vulgarism low-cost inspection psoriasis, what is worth the clinical promotion. Because it is good with skin lesions subsided rapidly, strong practicability, patient compliance and better tolerance, good curative effect, and no obvious toxic side effect and other advantages.更多还原