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早期子宫内膜癌淋巴结切除术的临床价值分析
Analysis of Clinical Value of the Resection of Lymph Nodes for Patients with Early Endometrial Carcinoma
【作者】 李娜;
【导师】 王丽华;
【作者基本信息】 上海交通大学 , 妇产科学, 2014, 硕士
【摘要】 子宫内膜癌是最常见的妇科肿瘤之一,淋巴结转移是其最主要的转移途径。自1988年起,FIGO分期由临床分期转为手术-病理分期。标准的手术分期包括盆腔淋巴结和腹主动脉淋巴结切除,然而对于早期子宫内膜癌患者是否常规行后腹膜淋巴结切除一直存在争议,本综述将对有关子宫内膜癌淋巴结切除的文献进行选择性述评,主要围绕后腹膜淋巴结切除的临床价值、适应症,切除范围、并发症,如何预测淋巴结转移等方面展开论述。最终得出的结论是:大多数研究证实后腹膜淋巴结切除对淋巴结转移低风险的患者无改善生存率的作用,而对中高风险的子宫内膜癌患者有提高生存率的作用,并对术后辅助治疗起到指导作用。同时关于前哨淋巴结切除的研究还处于初级阶段,尚不能代替系统性淋巴结切除术。
【Abstract】 Endometrial carcinoma is one of the most commongynecologic tumors, lymph node metastasis is the most important route ofmetastasis, Since1988,the FIGO staging has changed into surgicalstaging system from clinical staging.Standard surgical staging systemincludes the resection of pelvic lymph nodes and para-aortic lymph nodes,but for patients of early endometrial cancer,the routine resection ofretroperitoneal lymph node is still controversial. This article is basedon a selective review of the pertinent literature。therefore, this reviewwill focus on the clinical value of Retroperitoneal lymph node excision,indications, extent of resection, complication, prediction of lymph nodemetastasis and other aspects.Finally, we come to conclusions asfollows:Most studies have found no improvement in survival for patientsof low-risk of lymph node metastasis.Never the less, studies have showthat lymphadenectomy can improve the survival of patients in high risk,and make postoperative adjuvant therapy more sensible. At the same timethe researches on the sentinel lymph node excision are still in its initialstage, which can not take the place of systematic lymphadenectomy
【Key words】 Early endometrial cancer; The resection ofretroperitoneal lymph nodes; metastasis; The sentinel lymph node;
- 【网络出版投稿人】 上海交通大学 【网络出版年期】2015年 07期
- 【分类号】R737.33
- 【下载频次】92