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弥散加权成像阳性与短暂性脑缺血发作临床特征间的关系及预后评估
Study of Relationship between Diffusion-weighted Imaging Positively and the Clinical Features and Prognosis of Transient Ischemic Attack Patients
【作者】 黄平；
【导师】 陈阳美；
【作者基本信息】 重庆医科大学 ， 神经病学， 2014， 硕士
【摘要】 目的：回顾性分析短暂性脑缺血发作患者中DWI阳性与其临床特征的关系及其预后。方法：选择2012年1月至2013年12月到武警重庆总队医院住院治疗的短暂性脑缺血发作患者100例，根据DWI的检查结果将其分为DWI阳性组及DWI阴性组，分别比较两组患者的相关危险因素、临床表现及预后转归。结果：通过单因素分析两组患者中的相关临床特征，发现颈动脉斑块、TIA持续时间大于1小时、1周内TIA发作次数大于等于2次具有临床统计学意义（P＜0.05），且通过随访3月发现DWI阳性组有8例发生缺血性脑血管病，DWI阴性组有5例发生缺血性脑血管病，DWI阳性组发病率明显高于DWI阴性组，P值小于0.05。结论：DWI阳性与颈动脉斑块、TIA持续时间、1周内TIA发作次数有关。DWI阳性者再发缺血性脑血管病的风险较DWI阴性者明显增高。
【Abstract】 Objective: To study the clinical features and prognosis of thetransient ischemic attack(TIA) patients whose diffusion-weightedimaging(DWI) is positive.Methods:100patients suffered from transient ischemic attack whocharged in The Armed Police Hospital of Chongqing were analyzedretrospectively from January2012to December2013. The DWI wasperformed in the hospital, all the100patients were divided into DWIpositive group and DWI negative group. The risk factors, clinical featuresand prognosis were analysed between the two groups.Results: Carotid artery atherosclerotic plaque, TIA last more than onehour, TIA were diagnosis more than or equal to twice one week areindependent risk factors which will cause DWI positively．There had8patients underwent the ischemic cerebrovascular disease in DWI positivegrop within3months,5in the DWI negative group. The prevalence ofischemic cerebrovascular disease is higher in the DWI positive group, P＜ 0.05.Conclusion: Carotid artery atherosclerotic plaque, duration andfrequency of TIA were main causes of DWI positively. DWI positive grouphas a high risk of ischemic cerebrovascular disease than negative group.
【Key words】 Diffusion-weighted imaging； Transient ischemic attack； Clinical features； Prognosis；