长沙地区功能性消化不良证型分布规律及相关因素分析

【作者】 李慧；

【导师】 蒋士生；

【作者基本信息】 湖南中医药大学 ， 中医内科学， 2014， 硕士

【摘要】 研究目的：探讨长沙地区功能性消化不良患者的发病规律,总结证型分布规律及相关因素之间关系的研究,为湖南地区解决功能性消化不良防病与治病问题提供参考。研究方法：在中医基本理论的指导下,通过查阅关于功能性消化不良疾病相对应的“痞满”、“胃痛”等古典文献、现代中医病因病机文献,并参照罗马Ⅲ分类体系的功能性消化不良诊断标准及2009年国家出版发行的《消化不良诊疗共识意见》,制定临床症候调查表,采用问卷调查方式,对2013年1月至2013年12月来我院就诊的功能性消化不良患者全面收集中医四诊及相关资料。一共收集了131例功能性消化不良患者的临床资料,建立数据库,使用SPSS16.0统计软件进行统计,分析相关性。研究结果：长沙地区功能性消化不良患者的人群分布：性别与证候分布的相关性进行了统计学分析,P<0.05；发病与年龄差异有统计学意义(P<0.05)；发病与民族差异有统计学意义(P<0.05)；发病与文化程度差异有统计学意义(P<0.05),与职业差异有统计学意义(P<0.05)；发病与Hp感染与否无统计学意义,但Hp阳性者占总数的36.64%,所占比例较高,仍需进一步研究；发病与诱因差异具有统计学意义(P<0.05)；发病与饮食偏嗜具有统计学意义(P<0.05)。症候学研究：功能性消化不良中医主症间差异具有统计学意义(P<0.05)；症候分布具有统计学意义(P<0.05),脾胃湿热证占38.17%,肝胃不和证27.48%,脾虚气滞证17.56%,脾胃虚寒证12.21%,寒热错杂证4.58%；诱发因素与中医分型有统计学意义(P<0.05)；饮食偏嗜与中医分型有关(P<0.05)。研究结论：1.性别、年龄、民族、文化程度、职业与功能性消化不良发病有关；2.功能性消化不良与Hp感染与否无关；3.功能性消化不良以胃脘胀痛为主症。4.功能性消化不良以脾胃湿热证为主。5.功能性消化不良证型与性别、诱因、饮食偏嗜有关。更多还原

【Abstract】 Objective:To investigate the incidence pattern in patients with functional dyspepsia in Changsha, and summarize the studies of the relationship between the distribution of syndromes and related factors for functional dyspepsia in Hunan province. And hope that this study will be Hunan of Chinese medical treatment of functional dyspepsia to provide a disease prevention and treatment ideas.Methods:The study will be under of the basic Chinese medicine, by consulting on the fullness of TCM literature and modern classical cause and pathogenesis and therapy literature about "piman"、"weitong" which is according to functional dyspepsia. Plus the reference to the Rome III classification system diagnostic criteria for functional dyspepsia and the Indigestion treatment consensus opinion which is published by national magazine in2009, to develop a clinical symptoms.By the way of questionnaires, collect the Chinese medical and related information of the functional dyspepsia patients of our hospital’s from January2013to December2013.Collected a total 131cases and established a database to analysis the correlation by using the statistical software for statistical of SPSS16.0.Results:1.The population distribution of functional dyspepsia patients in Changsha, the statistical analysis between gender and syndromes correlation distribution showed no difference (P<0.05); the difference has statistically significant between age and onset (P<0.05); the difference has statistically significant between incidence and ethnic (P<0.05); the difference has statistically significant between incidence and degree of cultural(P<0.05); the difference has statistically significant between incidence and occupational(P<0.05); the difference has not statistically significant between incidence and Hp infection or not(P>0.05),but Hp positive accounted for36.64%, hold a high proportion, need further research; the difference has statistically significant between incidence and incentive(P<0.05);the difference has statistically significant between incidence and partial addicted to diet(P<0.05).2. Syndrome research:A statistically significant difference between the main symptoms of functional dyspepsia(P<0.05); the difference has statistically significant between symptom distribution(P<0.05),Spleen syndrome accounted for38.17%,Disharmony of liver and certified accounted for27.48%,Spleen qi stagnation accounted for17.56%,Spleen Deficiency syndrome accounted for12.21%,Mixed cold and heat syndrome accounted for4.58%.The difference has statistically significant between factors and TCM typing (P<0.05);partial addicted to diet and TCM Types have relationship (P<0.05)Conclusion:1.It is related between gender, age, ethnicity, education level, occupation and functional dyspepsia pathogenesis;2. Functional dyspepsia has nothing to do with Hp infection or not.3. Functional Dyspepsia’ syndrome based on epigastric pain.4. Functional dyspepsia’ syndrome based on spleen card based.5. Functional dyspepsia’ syndrome has something with gender, incentives, partial addicted to diet更多还原