【作者】 李金平；

【导师】 张爱华；

【作者基本信息】 兰州理工大学 ， 控制理论与控制工程， 2012， 硕士

【摘要】 脉搏信号在中医诊断中被称为脉象信息，蕴藏着丰富的人体生理和病理信息。客观准确地检测脉搏信号对于预测、诊断人体生理和病理情况有着相当重要的意义。然而，传统脉诊的信息不定量、模糊、主观性强等缺点，限制了中医脉诊的客观化，也成为制约脉诊学应用发展的主要因素。随着科学技术的不断发展，尤其生物医学、生物物理学、数学、计算机技术和数字图像处理等向医学领域的渗透，国内外越来越多的学者开始关注脉诊客观化研究，并对脉搏的检测、描述等做了大量的研究。脉诊客观化研究还表明，脉搏搏动除了含有压力搏动的信息之外，还包含管腔容积、血流速度、血压以及脉管的三维运动等多种信息。课题组从仿生学角度出发，模拟中医切脉过程，提出了新的基于图像化的脉象采集方法，研制了一种新型支架式脉象采集装置，利用高分辨率、高速摄像头在照明环境下采集表征桡动脉搏动的网格化薄膜运动，该装置初步达到了采集多维、动态信息的目的。本课题主要采用了视觉测量的思想改进了脉象采集装置，对传感器探头薄膜以及最佳测脉压力的定量化检测都做了较为完善的改进，并通过采集的人体桡动脉动态图像来表征脉搏信息。本课题运用三维运动分析方法，根据特征点匹配方法和光流法，描述了薄膜形变的一般三维运动方程，并对脉搏在三维空间中的变化进行分析。然后建立了空间位移测量原理模型，推导出了探测触头薄膜网格节点在Z轴方向上的位移量计算公式，并提出了基于光流法、空间位移测量、网格面积法、图像局部熵等脉搏图像三维重构方法。本课题中以上海中医药大学MM-3脉象模型作为被试对象，对其产生的平、滑、迟、濡四种脉象进行了三维重构。结果表明，从脉搏搏动的三维图像中我们可以获得更多地较为客观的脉象特征信息。总之，利用脉搏图像传感器，可以获得比其它传统脉搏传感器更加全面的脉象信息，而且能够实现脉搏图像的三维重构，这为脉诊客观化的研究以及脉象分析提供了新的思路和方法。更多还原

【Abstract】 Pulse signal known as the pulse information in traditional Chinese medicine,contains a wealth of human physiological and pathological information. So accuratelydetect the pulse signal has great significant for predicting and diagnosing of humanphysiological and pathological conditions. However, the information of the traditionalpulse diagnosis is vague, not quantitative and strongly subjective, which limits theobjectivity of traditional Chinese medicine diagnosis, and is also the constraints of thepulse diagnosis applications and development. With the development of science andtechnology, as well as the penetration of biomedicine, mathematics, biological physics,computer technology and digital image processing and so on to the field of traditionalChinese medicine. At home and abroad，growing number of scholars began to payattention to the pulse of objective research and did a lot of researches on the detectionand description of the pulse signal. Pulse objective studies have shown that the pulsethrob not only contains the information of pressure pulsation, but also contains theluminal volume, blood flow velocity and vascular three-dimensional motion of avariety of information.This research simulates pulse-taking of traditional Chinese medicine from the angleof bionics, and puts forward a new method about pulse condition collection based onthe visualization, the authors developed a new type of scaffolding pulse conditioncollection equipment, using high resolution, high speed cameras in lightingenvironment acquisition characterization of the radial pulse grids film movement, thedevice has reached a preliminary purpose of collecting multi-dimensional and dynamicinformation. Therefore, we improve the pulse collecting device with the idea of visualmeasurement, improve the quantitative detection of sensor probe film and the bestmeasure of the pulse pressure, and use acquisition of pulse dynamic image to obtainthe pulse information signal. In this paper, we use three-dimensional motion analysismethod to describe film deformation of three-dimensional equations of motionaccording to the feature point matching method and the optical flow method, andanalysis pulse changes in three-dimensional space. Then established the model of thespatial displacement measurement principle, derive the formula of displacement of theprobe contact film grid node in the Z direction, and put forward three-dimensionalreconstruction methods of pulse image which based on the optical flow method, spatialdisplacement measurement, the grid area, image local entropy. we use MM-3pulse hand which produced by Shanghai University of Traditional Chinese Medicine as thesubject, and then achieves three-dimensional reconstruction of flat, slip, late, moistenthe four kinds of pulse. The results show that, we can get more objective informationof pulse characteristics from the three-dimensional images of the pulse.In short, using the pulse image sensor can obtain more comprehensive pulseinformation than the other traditional pulse sensors, and can achieve thethree-dimensional reconstruction of the image of the pulse,which provide new ideasand methods for the objectivity study and analysis of the pulse.更多还原