【作者】 王俊；

【导师】 袁贤瑞；

【作者基本信息】 中南大学 ， 神经外科， 2008， 硕士

【摘要】 目的:了解颅咽管瘤的不同起源及术中垂体柄保留对术后水、盐代谢及血糖变化的影响,寻找影响该类情况的因素。方法:对43例颅咽管瘤显微手术进行了回顾性研究,记录了患者术后资料、术后水、盐代谢及血糖、体温及术中垂体柄保留情况,运用SPSS13.0统计软件对结果进行分析。结果:43例患者,40例肿瘤全切除,平均全切率93.02%。术中解剖保留垂体柄23例,垂体柄保留率53.48%。无死亡病例,出院时一般情况均良好。术中垂体柄得到保留的患者术后血糖、尿量情况优于未保留者,两者之间的差别有统计学意义。结论:颅咽管瘤术后水、盐代谢及血糖的紊乱类型以及程度与病灶的起源部位之间未发现明显的关系,术中垂体柄保留对预防术后水、盐代谢及血糖紊乱有积极意义。术中应该注重显微操作以及对周围重要神经结构尤其是垂体柄保留。更多还原

【Abstract】 Objective To detect the impact to the type and degree of water and salt metabolism disturbance and disorders of glucose resulted by micro-neurosurgery of different origination of craniopharygioma and the preservation of pituitary stalk and then discuss the determinants of this situation.Method we conduct a retro-perspective research that is the analysis of the data of water,salt and glucose metabolism and preservation of pituitary stalk of 43 post-operative patients of craniopharygioma,which is disposed by SPSS 13.0 for statistics.Result 40 of the patients received total resection while the total resection rate is 93.02%.Among these patients,with the pituitary stalk reservation rate at 53.48%,9 received total reservation of pituitary stalk, while 14 received partial reservation of pituitary stalk.There is no tumor recurrence and dead case,while all the patients’ general condition and life sign is stable.The diabetes insipidus and water and salt metabolic disturbance are easy to amend.Conclusion The type and degree of water and salt metabolic disturbance and glucose disorders of post-operative patient of craniopharygioma is no significance with the different location of tumors. The determinants of the type and degree of water and salt metabolic disturbance and glucose disorders of post-operative patient of craniopharygioma is the nicety of micro-neurosurgery and the preservation of periphery anatomy structure,especially the pituitary stalk.更多还原