【作者】 李婷；

【导师】 周亦农；

【作者基本信息】 广州中医药大学 ， 中医外科学， 2009， 硕士

【摘要】 本研究观察并分析了滋阴清热解毒法对女性青春期后痤疮的临床疗效及对女性青春期后痤疮患者血清睾酮值的影响等问题,为滋阴清热解毒法治疗女性青春期后痤疮提供了一定的依据。目的:观察滋阴清热解毒法对女性青春期后痤疮的临床疗效及对血清睾酮值的影响。方法:根据纳入标准收集病例90例,采用随机数字表的方法结合患者就诊顺序将患者分配治疗组60人和对照组30人,治疗组内服滋阴清热解毒自拟方,对照组口服清热暗疮片,2组均配合棉签法液氮冷冻治疗,观察周期为1个月(2周为一疗程),观察临床疗效并在治疗前后测定血清睾酮值。所有数据应用SPSS13.0统计软件进行分析。结果:综合疗效方面,治疗组疗效优于对照组,差异有显著性(P＜0.05);中医证候疗效方面,治疗组疗效优于对照组,差异有非常显著性意义(P＜0.01)。治疗组治疗后血清睾酮值明显降低,差异具有显著性(P＜0.05)。结论:滋阴清热解毒法治疗女性青春期后痤疮疗效确切,可降低血清睾酮值。滋阴清热解毒法安全有效,值得临床推广。更多还原

【Abstract】 In This study,clinical effects and the changes of serum level of testosterone by treatment method of replenishing yin and removing heat and toxic.It can provide the basis for treatment of female post-adolescent acne by method of replenishing yin and removing heat and toxic material by observing and analyzing the clinical effects of female post-adolescent ache.Objective:To investigate the clinical effects of treatment method of replenishing yin and removing heat and toxic material in the treating female post-adolescent acne,to explore the changes of serum testosterone levels.Methods:The patients were randomly divided into two groups.60 cases in treatment group,treated with method of replenishing yin and removing heat and toxic material,30 cases in control group,treated with removing heat acne tablets.The patients of two group were wiped liquid nitrogen.The course of treatment was one months(a course of treatment for two weeks).To observe the clinical effects and to measure the changes of Serum Testosterone levels.The data are analysised by the statistical software named spss 13.0.Results:Compared with the control group,the total effective rate in the treated group was more effective,comparison between them showed difference,there was statistics difference between them(P＜0.05).Compared with the control group,the TCM Syndrome in the treated group was more effective,comparison between them showed very significant difference,there was very significant statistics difference between them(P＜0.01).The treated group after the treatment,serum level Of testosterone showed lower compared with the treated group before the treatment(P＜0.05). Conclusion:Treatment method of replenishing yin and removing heat and toxic material could lower the serum level of testosteroneand with few adverse reaction treating female post-adolescent,lt is effective and safe,and worth to recommended in clinical application.更多还原