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黄芪党参桂枝汤合半夏厚朴汤治疗功能性消化不良脾虚肝郁证的临床研究
【作者】 李庆莉；
【导师】 梁超；
【作者基本信息】 成都中医药大学 ， 中医内科学， 2007， 硕士
【摘要】 功能性消化不良(functional dyspepsia,FD)是指非器质性病变引起的一组常见的消化系统症候群。其病因和发病机制尚未明确,现代医学尚无特效疗法。近年来中医中药对功能性消化不良的治疗进行了大量的研究,取得了可喜的进步和较为满意的疗效。本文查阅了大量的中西医关于功能性消化不良的文献资料,收集整理了现代医学在功能性消化不良流行病学、发病机制、治疗方面的研究进展,以及中医历代对功能性消化不良的认识和最近中医在辨证论治、治法方药等方面的研究进展。在总结导师对功能性消化不良诊疗经验的基础上,我们进行了本项研究。目的:观察“黄芪党参桂枝汤”与“半夏厚朴汤”合用治疗功能性消化不良脾虚肝郁证的临床疗效,为减轻患者痛苦提供治疗方法,为临床推广提供依据。方法:将符合诊断标准的60例病人随机分为三组。治疗组20例,服用黄芪党参桂枝汤合半夏厚朴汤;对照组A20例,服用黄芪党参桂枝汤;对照组B20例,服用半夏厚朴汤。4周为一疗程。观察治疗组治疗前后中医症状总疗效和单项症状疗效,以及与两个对照组的比较情况。结果:60例患者中56例完成整个疗程。三组治疗前后总体评分均有显著性差异(P＜0.05)。治疗组总体疗效有效率94.74%,而对照组A和对照组B的有效率分别为83.33%、78.95%。结论:黄芪党参桂枝汤合半夏厚朴汤能够很好地改善功能性消化不良脾虚肝郁证患者的临床证候。
【Abstract】 Functional dyspepsia(FD) is a common group of digestive system’s symptoms which was caused by non-organic diseases.Its etiology is still uncertain and there is no very effective method to treat it for the time being,in recent years,numerous treatments of FD have been studied by Traditional Chinese Medicine(TCM),and have achieved satisfactory effect and progress.This study consults a lot of therecord about FD,collects the records of West Medicine in the epidemiology,etiology,treatment and its outlook,as well as the understanding of ancient documents and the record of.the latest developments of TCM in the treatment based on differentiation,therapy,prescription.After summing up my tutor’s experience,we carried out the clinical study.Objective:This study is to observe the clinical treatment effect of lluangqi-Dangshen-Guizhi decoction together with Banxia-Houpo decoction on FD of Spleen-deficiency and Liver-Qi-stagnation.This study can afford new methods of treatment to alleviate the patient’s sufferings.And it also can afford evidence for clinical promotion.Methods:In the clinical study,60 patients of FD were divided into three groups randomly.There were 20 patients in the treatment group,treated by lluangqi-Dangshen-Guizhi decoction together with Banxia-Houpo decoction. There were also 20 patients in the’control group A,treated by lluangqi-Dangshen-Guizhi decoction.And 20 patients were in the control group B,treated by Banxia-Houpo decoction.The course of treatment was 4 weeks by the three groups.The treatment.group’s clinical symptoms of TCM were evaluated before and after the treatment,comparing with the two control group.Results:There were 56 patients finished the whole course of treatment in 60 patients.The three groups all improved the overall symptoms effectly.The overall effectiye rata was 94.74%of the treatment group comparing with 83.33%and 78.95%of the two control groups.Conclusion:Huangqi-Dangshen-Guizhi decoction together with Banxia-Houpo decoction could obviously improve the patients’ clinical symptoms.