【作者】 刘大蔚；

【导师】 冯亚青；

【作者基本信息】 天津大学 ， 应用化学， 2007， 硕士

【摘要】 吡啶是一种重要的化工基础原料,吡啶及其衍生物逐渐的被广泛地应用于农药,医药,日化产品等各个领域。本论文主要研究了以四氢糠醇为原料合成吡啶的工艺。在高温条件下,以四氢糠醇和氨气为原料在管式固定床中,经金属氧化物催化剂催化制得吡啶。针对前期工作采用的催化剂载体成本过高问题,研究了条状γ-三氧化二铝,Al-S（i1）,Al-Si（2）三种催化剂载体的替代工作。其中负载10% MoO₃/ Al₂O₃,反应温度550℃,四氢糠醇流量0.1mL/min,n（THFA）:n（NH₃）=1:4的条状γ-三氧化二铝,THFA转化率为98.33%,吡啶选择性为72.23%,吡啶的收率为71.02%。对主催化剂进行了研究,确定了10% MoO₃/ Al₂O₃为最佳的主催化剂。并研究了多元复合催化剂,通过向主催化剂中添加助催化剂,进一步改善了催化性能。其中在反应温度550℃,四氢糠醇流量0.1mL/min,n（THFA）:n（NH₃）=1:4条件下,采用10%MoO₃-3%Ce₂O₃-2%MgO,THFA转化率为99.12%,吡啶选择性为87.09%,吡啶的收率为86.32%。另外还对金属氧化物催化剂的寿命进行了研究。在反应进行到62h时,吡啶的收率大概下降至原先的一半。更多还原

【Abstract】 Pyridine is an important basic chemical material. Pyridine and its derivatives are widely used in fields such as pesticide, medicine and cosmetics.The process for the synthesis of pyridine using tetrahydrofurfuryl alcohol（THFA）as material was researched in this article. Pyridine was prepared by THFA and ammonia in a tubular fixed bed reactor under effects of metallic oxide catalysts and high temperature. In order to deal with the high cost of catalyst carriers applied in previous works, three new catalyst carriers-stripγ-Al₂O₃, Al-Si（1）,Al-Si（2）were researched for replacement. The rate of conversion of THFA was 98.33%, selectivity of pyridine was 72.23%, the reaction yield of pyridine was71.02% with 10% MoO₃/ Al₂O₃ loaded on stripγ-Al₂O₃, when reacting temperature was 550℃, the flow rate of THFA was 0.1mL/min and n（THFA）:n（NH₃）=1:4. Different major catalysts were researched, 10% MoO₃/ Al₂O₃ was affirmed as the best major catalyst. Multiplex catalysts were also researched, the properties of catalysts were further improved by the add of cocatalyst into major catalyst. The rate of conversion of THFA was99.12%, selectivity of pyridine was87.09%, the reaction yield of pyridine was 86.32% with 10%MoO₃-3%Ce₂O₃-2%MgO as the catalyst, when reacting temperature was 550℃, the flow rate of THFA was 0.1mL/min and n（THFA）:n（NH₃）=1:4.The lifetime of metallic oxide catalysts was also researched. The yield of pyridine decreased to about half of the previous yield after a reaction time of 62h.更多还原