从体质学说研究化痰祛湿法对缺血性中风的治疗作用

【作者】 郭兴富；

【导师】 过伟峰；

【作者基本信息】 南京中医药大学 ， 中医内科临床， 2006， 硕士

【摘要】 中风是严重威胁中老年人生命健康的常见疾病之一，随着我国人口老龄化趋势的不断加速，其危害日益突出。本文系统回顾总结了古今医家对中风病病因、病性、征候等方面的认识，并对中医体质学说的理论和实践研究进行分析总结，试图从体质学说角度对中风病(脑梗死)进行研究和探索。根据文献报道和临床经验，发现痰湿体质患者逐年增多，痰证成为中风病的重要证型之一，故本研究从化痰祛湿立法，治疗痰湿体质的缺血性中风患者，观察其治疗效果及对痰湿体质的改善情况。 本研究按照全国第四次脑血管病学术会议制定的脑血管病诊断标准，选取痰湿体质的缺血性中风患者为治疗对象。以温胆汤加减方治疗脑梗死患者24例，并设20例未服中药的常规治疗组进行对照，分别进行治疗前后的神经功能缺损评分、痰湿体质评分、生活质量及日常生活能力量表评分，及血脂、血液流变学等指标的对比。观察结果：经治疗一个疗程(14天)后，治疗组临床有效16例，无效8例，总有效率66.7％；对照组有效12例，无效8例，总有效率60.0％。两组患者神经功能缺损评分、日常生活能力量表评分均有不同程度的改善，而治疗组痰湿体质评分、生活质量及日常生活能力量表评分改善程度较对照组明显，两组比较有显著差异(P＜0.05)。 结论：化痰祛湿法对痰湿体质型脑梗死患者有较好的疗效，能提高患者的日常生活能力、生活质量，改善痰湿体质。更多还原

【Abstract】 Cerebral infarction(CI) is a common disease that threats people’s health seriously, we review and summarize the recognization of ancident Chinese medicine and morden development of CI,we also review the somatic substances and try to study CI with it Base on the theoretical views and clinical experience of CI,Tan zheng is the major type of CI.So we put forword Huatan Qushi Decoction (HTQYD) is an important therapeutic method of CI.Forty-two patients with cerebral infarct were randomly divided into two groups. The control group (20cases) were treated with clinical treatment. On the basis of conventional treatment western medicine, the HTQYD was given to the treated group (24 cases) additionally. The neurofunction deficit score, the somatic substances score, Activity of daily life(ADL),the blood lipid and hemorrheologic character were determined in pre-treatment and post 14 days respectively.As a Result,There were the significant improve in the both of the neurofunction deficit scores after treatment. The difference before and after treatment was no significance (P>0.05). the somatic substances score in the treated group decreased from 50.85±19.78 to 30.75±19.11 (P<0.01).The score in the control group decreased from 49.41±17.93 to 44.18±22.84 (P<0.05). The difference was markedly significant (P<0.01). The Qil scores and ADL scores in each groups rised had a significant difference(P<0.05),the process of scores in the treated group were obviously superior to that in the control group.Conclusion: The treatment of Huatan Qushi Decoction (HTQYD) may obviously improve the somatic substances scores ,QIL scores and ADL scores.更多还原