【作者】 王波；

【导师】 蔡方成；

【作者基本信息】 重庆医科大学 ， 儿科学， 2006， 硕士

【摘要】 第一部分肌阵挛的临床与电生理研究目的:应用多项神经电生理技术观测不同起源和性质肌阵挛的临床-电生理鉴别要点。方法:应用视频脑电-肌电多导记录(video electroencephalogram electromyogram polygraphic recordings,VEEG-EMG)、抽搐逆向锁定的脑电平均技术(jerk-locked back averaging,JLA)以及短潜伏期躯体感觉诱发电位(short latency somatosensory evoked potential,SSEP),对32例肌阵挛患儿进行临床和多项电生理的实时联合记录分析。同时,根据肌阵挛起源部位的判断标准,将32例患儿分为皮层组、皮层下组及其他肌阵挛组;根据肌阵挛性质的判断标准,分为癫痫性和非癫痫性肌阵挛。结果: 32例患儿中,皮层组14例,皮层下组14例,其他肌阵挛组4例。(1)皮层组:11例患儿的肌阵挛呈局灶性或多灶性发作,另3例除局灶性发作外还有全身性肌阵挛。11例患儿呈非节律性肌阵挛,3例还伴有节律性发作。10例对刺激高度敏感,4例对刺激不敏感。肌阵挛同步EMG时程为15±4 ms～46±8 ms。EEG背景活动5例正常,更多还原

【Abstract】 Part One A Study On Clinical And Electrophysiological Features Of MyoclonusObjective: To explore the clinical and electrophysiological characteristics of myoclonus from different generating locations and their properties by polyneuroelectrophysiological tests.Methods: 32 myoclonic patients were analyzed by video electroencephalogram electromyogram polygraphic recordings (VEEG-EMG), jerk-locked back averaging (JLA) and short latency somatosensory evoked potential (SSEP). They were classified into cortical myoclonus (CM), subcortical myoclonus (SCM), and other myoclonus group according to their generating locations, and also were classified into epileptic and nonepileptic myoclonus based on the different properties of various myoclonus.Results: 32 patients were observed, including 14 cases of CM, 14 cases of SCM and 3 cases of other myoclonus. (1) CM: myoclonic seizures更多还原