【作者】 刘芸；

【导师】 戴礼兴；

【作者基本信息】 苏州大学 ， 材料学， 2006， 硕士

【摘要】 本课题应用了近年来研究较多的静电纺丝方法,对丝素/聚乙烯醇共混纳米纤维的纺制进行了实验研究,着眼于再生丝素纤维的共混改性研究,添加聚乙烯醇组分改善再生丝素材料的脆性缺陷,并且,利用丝素和聚乙烯醇良好的生物相容性、生物降解性,以及纳米纤维所组成的非织造织物所具备的高孔隙率,为其成为一种性能优异的生物医用材料提供了可能。本文以丝素为主,与聚乙烯醇共混,在一定程度上改善了再生丝素材料的物理机械性能,同时借助静电纺丝方法制得共混纳米纤维无纺织物,并对其共混溶液的相容性、可纺性、成型特点进行了研究,对纳米纤维的结构性能进行了初步探讨。本实验主要分为三个部分:一,研究了丝素/聚乙烯醇共混纺丝液的相容及可纺性情况,结果表明,甲酸溶剂能使所获得的共混纺丝液具备相对较大的组分相容性及稳定性,但纺丝液的共混搅拌时间不宜过长,以20至30分钟为宜,纺丝液共混配比80/20为佳,且添加少量的丙三醇将有利于两组分间的相容。同时,通过实验可知,溶液的粘度、电导率等性质对纺丝液的喷射过程影响较大,而纳米纤维的最终成型仍更多地由纺丝溶剂的挥发性及纺丝液共混配比来主导。二,研究了该共混体系进行静电纺丝的情况,结果表明,聚乙烯醇的加入,能使再生丝素材料的柔韧性得到一定程度的改善。当共混配比为80/20时,所得样品纤维形态较为均匀理想;同时,甲酸溶剂的强挥发性也在很大程度上帮助了喷纺纤维的快速成型。挥发性较差的丙三醇组分少量添加有利于降低纳米纤维的纤度及均匀性,但此时不宜较多添加,影响纺丝溶剂的挥发及纤维成型。此外,纺丝电压以稍高于临界电压的10KV为宜,避免过高电压所引起的急速喷射,减少纤维的拉伸成型时间,同时,纺丝的喷射距离也应保持适中。三,对所制得的丝素/聚乙烯醇共混纳米纤维的红外谱图以及DTA-TG热分析曲线进行了初步的探讨,结果表明,有赖于静电纺丝工艺使纳米纤维快速拉伸成型的特点,使实验所得的共混丝素/聚乙烯醇纳米纤维较由常规纺丝工艺所制备的纤维产品更多还原

【Abstract】 In this paper, SF(silk fibroin)/PVA(polyvinyl alcohol) blending nanofibers were prepared via electrospinning in order to improve RSF material’s physical properties and broaden its potential applications. The rigidity of RSF materials could be improved by adding PVA which has flexible chains. And the porous structure of SF/PVA non-woven nanofibers via electronspinning as well as their properties of biocompatibility and biodegradation possibly be suitable for biomaterials. The compatibility, spinnability and fiber formation of blending solution were studied, and the fiber structure and properties were also primarily discussed in the paper.The paper was divided into three parts:1.The spinning solution of SF/PVA was discussed. The results showed that the uniformity and stability of SF/PVA solution could be improved by formic acid solvent. And the suitable blending time would be 20～30 minutes. And the blending ratio 80/20 resulted in improved miscibility of spinning solution. In addition, the compatibility of blending solution could also be improved by adding glycerine. Meanwhile, the status of spinning jet would be affected mainly by viscosity and conductance of the spinning solution while the formation of nanofibers would be decided largely by the blending ratio and volatility of spinning solvent.2. The influence factors of SF/PVA nanofibers’fomation by electronspinning were studied. The results showed that the flexibility of SF could be improved by adding PVA and the blending ratio of 80/20 would result in better spinnability. However, glycerine is not so good to use much in electronspinning for its difficulties in volatility. And a relatively low voltage of 10KV supplied enough power and time for fiber drawing and formation. The fiber collecting distance should also be kept suitable.3. The structure and properties of SF/PVA nanofibers were primarily investigated更多还原