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OCD执行功能与共病抑郁的关系及其反应抑制缺陷的研究

An Study on Relationship between OCD’s Executive Function and Comorbid Depression and Its Response Inhibition Deficits

【作者】 季春梅

【导师】 蔡厚德;

【作者基本信息】 南京师范大学 , 基础心理学, 2006, 硕士

【摘要】 目前关于OCD病人执行功能障碍和反应抑制缺陷之间的关系更多的是基于研究者的理论假设,本研究将共病抑郁作为一个重要变量,力图进一步揭示OCD病人执行功能障碍和反应抑制缺陷之间的关系,尤其是在知觉水平和反应水平上的抑制能力对执行功能的影响,以期加深对OCD病人认知机制的认识和理解。 本研究采用威斯康星卡片分类测验、刺激-刺激和刺激-反应相容性实验,对48名强迫症病人和48名正常被试做对照研究。结果发现:(1) 只有伴随抑郁的强迫症病人才有明显的执行功能障碍。(2) OCD病人存在抑制缺陷,尤其体现在反应水平的抑制缺陷上。(3) 伴随抑郁的病人组在反应水平上的抑制功能缺损要大于无抑郁的病人组。(4) 在三个SOA条件下,只有在OmsSOA时,病人的反应一致性效应显著。

【Abstract】 Recently the relation between response inhibition deficits and executive function default on OCD is more based on the theorist’s hypothesis. Using comorbid depression as an important variable, the present study is to determine whether OCD subjects exhibit deficits in behavioral and cognitive inhibition compared with a control group and effects on executive function , so as to further understand OCD’s mechanism of cognition.48 OCD patients and 48 healthy subjects are administered Wisconsin Card Sorting Test (WCST) 、 stimulus-stimulus and stimulus- response consistentexperiment. The analysis showed that: ①OCD patients, in particular ,with comorbid depression demonstrated impaired performance on tests of executive function. ②OCD patients exhibit deficits in inhibition, especially in behavioural inhibition. ③ Inhibition deficits of patients with comorbid depression in behavior is more serious than patients without depression. ④ Under the condition Of SOA0ms, significant consistent response effects are observed in patients, however, the effects are not found in patients under the condition of SOA300ms and SOA600ms

  • 【分类号】B842
  • 【被引频次】2
  • 【下载频次】193
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