【作者】 李宇；

【导师】 姜潮；

【作者基本信息】 大连医科大学 ， 流行病与卫生统计学， 2006， 硕士

【摘要】 研究目的:本调查主要研究普通人群中情感障碍、焦虑障碍和酒精使用障碍的单病和共病状态的危险因素。对象与方法:数据来源于辽宁省精神卫生调查,采用了回顾性流行病学研究方法,在13,359位18-65岁的辽宁地区普通人群中,采用CIDI方法进行访谈。对结果采用SPSS 13.0进行统计分析,并使用X2检验和Logistic回归方法比较了单病、共病与无病者,以及单病与共病者之间的社会人口学的特征。结果:1.情感障碍只有59.12%是以单纯疾病形式出现,情感共病障碍中情感共病焦虑障碍为31.86%,单纯焦虑障碍和单纯酒精使用障碍的患病率分别为72.91%和77.25%。最常见的共病形式是情感与焦虑共病障碍,它与5个社会人口学变量有相关性。吸烟者患单纯焦虑和焦虑共病情感障碍的危险度降低。2.单纯的情感、焦虑以及情感与焦虑共病障碍在女性中更常见,酒精使用障碍的单病和共病状态在男性中更常见。单纯情感、焦虑和酒精使用障碍、情感共病焦虑或酒精使用障碍的患病率都随着年龄增长而增加(18-55岁),55岁以后稍有下降。单纯焦虑和焦虑共病酒精使用障碍农村多于城市,单纯情感和情感共病酒精使用障碍城市多于农村。单纯情感、焦虑以及两者共病障碍的患病率都随教育水平提高而降低。离婚、丧偶或分居等不和谐家庭人群中患单纯情感、焦虑及两者共病,以及情感共病酒精使用障碍的危险度最高。收入因素只和单纯情感障碍以及焦虑障碍有相关性,两者在低收入人群中患病的危险度升高;而酒精使用障碍和经济状况无明显相关性。吸烟因素与大部分疾病状态有相关性,吸烟人群中患单纯酒精使用、情感共病酒精使用障碍,以及情感、焦虑、酒精使用三者共病障碍的危险度升高。3.单纯情感障碍与除吸烟外的所有因素均有显著性相关,危险因更多还原

【Abstract】 Objective: This study examined risk factor profiles of pure and comorbid mood, anxiety, and alcohol use disorders in the general population.Method: Data were derived from Liaoning Province Mental Health Survey, a prospective epidemiologic study in which a representative sample of 13,359 adults age 18–65 years were interviewed with the Composite International Diagnostic Interview ( CIDI ). Logistic regression was used to compare subjects with a diagnosis of pure and comorbid disorders with nonpsychopathological comparison subjects on sociodemographic characteristics.Results: 59.12% of the subjects with pure mood disorder, 31.86% of those with an anxiety disorder, 72.91% and 77.25% of those with an anxiety and alcohol use exhibited the disorder in the pure form respectively. Comorbid anxiety and mood disorder, the most prevalent comorbid condition, showed associations with five sociodemographic factors investigated. Smoking can reduce the risk of pure anxiety disorder and comorbid anxiety and mood disorder. Pure mood disorder, anxiety disorder and comorbid mood and anxiety disorder are common in female, while pure and comorbid form of alcohol disorders are common in male. The prevalence of pure mood, anxiety, alcohol use, comorbid mood and anxiety or alcohol use disorder increased with age(18-55), and decreased when age>55. Pure anxiety disorder and comorbid anxiety and alcohol use disorder are common in rural; while pure mood disorder and comorbid mood and alcohol disorder are common in urban. The prevalence of pure mood, anxiety, and comorbid mood and anxiety disorders decreased with更多还原