【作者】 张薇；

【导师】 滕召胜；

【作者基本信息】 湖南大学 ， 测试计量技术及仪器， 2006， 硕士

【摘要】 血吸虫病严重危害人们身体健康,导致大量患者劳动力丧失;严重影响了经济发展,带来的不安定因素阻碍了社会的和谐与稳定。因此,血吸虫的防治具有重大意义。杀灭血吸虫尾蚴,切断血吸虫的感染途径,破坏其生命周期,是彻底根除血吸虫病的最有力方法。针对常用的化学药物杀灭法存在的易使尾蚴产生抗药性、水域宽广致使药效降低、污染环境、毒杀其它生物等弊端,本文提出了一种利用高压脉冲电场杀灭血吸虫尾蚴的新方法,探讨了这种电子杀灭方法的可行性,分别研究了采用锐形电极和平板电极的血吸虫尾蚴杀灭机理,分析了影响尾蚴杀灭效果的各种因素,介绍了实验阶段血吸虫尾蚴高压脉冲电场杀灭系统的构成,指出了系统研制和试验过程中需要充分考虑的安全性问题。本文共分为五章。第一章描述血吸虫的生长周期及分布、血吸虫对宿主的危害,说明杀灭血吸虫的重大意义,指出本文的研究背景和主要内容。第二章阐述现有的直接和间接血吸虫杀灭技术的基本原理、特点和适用场合,介绍血吸虫杀灭技术研究现状,指出血吸虫杀灭方法的发展趋势。第三章主要介绍尾蚴的超微结构,探讨采用血吸虫尾蚴高压脉冲电场杀灭技术的可行性,研究血吸虫尾蚴高压脉冲电场杀灭技术的机理,分析影响杀灭效果的电场参数、处理环境和生物特性因素。第四章介绍血吸虫尾蚴高压脉冲电场杀灭系统的功能和组成,探讨电极材料的选取、电极的吸附效应与改善方法。第五章介绍系统在防尾蚴感染、防电磁波、防静电和高压区域隔离方面的安全性设计。最后结论部分总结文章的创新和不足。血吸虫尾蚴高压脉冲电场杀灭方法能避免传统化学药物杀灭血吸虫尾蚴的不足,还具有水面杀菌、净化水域的环保效果,具有积极的社会意义和广阔的应用前景,为消灭血吸虫探究了一种新方法,可望为绿色血防开辟崭新途径。更多还原

【Abstract】 Schistosomiasis seriously endangers people’s health, loses the patients’labour, seriously affects economic development also social harmony and stability. Therefore, it is significant to prevent and control the schistosome. Elimination schistosome cercaria can cut off the infection channel of schistosome and destroy its lifecycle, consequently prevent people from infecting. It is the most powerful means of eradicating schistosomiasis.Current method of elimination cercaria is mainly the chemical method which has many disadvantages such as drug resistance, drug dilutedness, environmental pollution and poisoning the other biology, etc. For these reasons, this paper poposed a new method of elimination through high-voltage pulsed electric field, discussed the feasibility of the new method, studied the elimination mechanisms of using different forms of electrodes, analyzed various factors which influences the effect of elimination and introduced the structure of high-voltage pulsed electric field system at the stage of laboratory. Moreover, this paper showed the security problems that should be considered during the research and experiment.This paper is divided into five chapters. The first chapter described the lifecycle, the distribution of schistosome, the harm of schistosome and the significance of elimination schistosome, then pointed out the background of this research and the main content of the entire paper. The second chapter illustated the basic principle of the schistosome elimination technology, also the characteristic and the suitable situation of the schistosome elimination technology, the research status of elimination technology and the trend of method which is used to eliminate schistosome are introduced. In the third chapter, the ultrastructure of cercaria is introduced, the feasibility of using high-voltage pulsed electric field to eliminate schistosome is discussed, elimination mechanism of high-voltage pulsed electric field is researched and the factors which affect the elimination effect are analyzed. The forth chapter presented the function and the structure of high-voltage pulsed electric field system, introduced how to select the electrode material and discussed the adsorption effect also the improvement method. In the last chapter, the security design of system is presented. The final part summarized the innovation and lack of this paper. The new mehod of elimination schistosome through the high-voltage pulsed更多还原