【作者】 马云翔；

【导师】 田福利；

【作者基本信息】 内蒙古大学 ， 有机化学， 2005， 硕士

【摘要】 本文通过使用乙醇对蒙椴树叶及木质部进行室温浸泡提取,再用系列有机溶剂(依次为石油醚、乙酸乙酯、乙醇)分别萃取得到蒙椴树叶和木质部石油醚提取物、乙酸乙酯提取物、乙醇提取物。利用柱层析、薄板层析、萃取、重结晶等分离提纯技术对上述提取物进行分离提纯,从中得到了7个化合物和一个烷烃混合物。通过红外光谱、元素分析、核磁共振氢谱、碳谱及采用二维核磁的HMQC、HMBC与COSY等技术,阐明了6个化合物的结构,分别为:蒲公英萜醇二十八碳酸酯、软木三萜酮、胡萝卜苷、三十五碳醇、β-谷甾醇、十九碳酸。在所得到的化合物中,在蒙椴化学成分的研究中,蒲公英萜醇二十八碳酸酯、胡萝卜苷、软木三萜酮、三十五碳醇、十九碳酸均为首次发现;β-谷甾醇为蒙椴木质部首次发现。通过对蒙椴树叶成分利用气相色谱-质谱(GC-MS)连用技术分析,确定出其中的45种化学成分,并通过标准峰面积法确定了它们的相对含量,已鉴定成分占总油状组分的80.35%,主要成分以脂肪酸、烷烃、醇类物质为主。对分离出的六个化合物及通过GC-MS鉴定出的化合物的性质及它们潜在的抗天牛活性进行了讨论。更多还原

【Abstract】 The leaves and woods of Tilia mongolica were extracted with ethanol. The extracts were partitioned following Petroleum ether, Ethyl acetate and Ethanol solvents. Purifaction of them was accompolished by column chromatograph, TLC and recrystallization. To date, seven compounds and one mixture including alkanes have been isolated from the extracts. Six structures of them were determined by IR, Element Analysis, ~1HNMR, ~13CNMR&DEPT, HMQC, HMBC, COSY of 2D NMR datas. They are Taraxeryl octacosanoic acetate, Friedelin, β-sitosterol, Dauvosterol, pentatriacontanol and Nondecanoic acid. Taraxeryl octacosanoic acetate, Friedelin, Dauvosterol, pentatriacontanol and Nondecanoic acid are detected for the first time in studying of Tilia mongolica. And β-sitosterol is detected for the first time in studying of Tilia mongolica wood. By GC-MS techniques, it is ascertained that forty-five kinds of chemical components were in the leaves of Tilia mongolica and they accounted for over 80.35 percent of total volatile oil. The properties and potential applications of the six compounds and forty-five components against Anolophora Glabripennis have been discussed.更多还原