【作者】 林永平；

【导师】 蔡坚勇； 谢树森；

【作者基本信息】 福建师范大学 ， 光学工程， 2005， 硕士

【摘要】 本文从医用光活检的基本理论出发,开展早期鼻咽癌荧光分光定位系统的研究,设计出该系统信号处理的软件。首先从系统的检测原理入手,概述了荧光光谱分析的原理,再介绍光活检技术,说明该系统所采用的检测方法,接着分析系统的光学设计以及系统外部硬件的设计方法。在此基础上,通过虚拟仪器的开发平台LabVIEW设计出与整个系统完善结合的信号处理软件。我们详细介绍该软件各个模块的功能,重点讨论了定标信号的处理方法与其可行性:对采集的数据信号与定标信号的同步问题进行研究,使用数据采集卡的数字触发采集功能来保证软硬件采集数据的同步性能:使用经典数值分析方法对数据进行处理,以多种方式进行显示,方便鼻咽癌数据的分析;可以随时保存采集到的荧光光谱曲线。该软件为以后鼻咽癌的光活检,尤其是定位技术提供了必要的处理方式和基础软件。 为了验证信号的同步性和波长定标的准确性,我们设计了软硬件同步测试实验,实验结果表明我们的软件系统不论是定标信号的定位性能,还是与系统硬件检测的同步性能都比较稳定,分析与显示功能强大,使用方便,可以用于早期鼻咽癌的诊断与定位。更多还原

【Abstract】 Based on researching medical optical biopsy of early nasopharyngeal carcinoma, we design the software on signal processing of fluorescence spectroscopy for diagnosis and localization of nasopharyngeal carcinoma. First, we analyze the theory of fluorescence spectrum. Second, we introduce the optical biopsy technique for nasopharyngeal carcinoma which is the detecting method for this system. Third, the optical and the hardware design are illustrated. Based on these theories, we design the software on signalprocessing by the virtual instrument design tool------LabVIEW. We present themodules on detail, the technique of calibration’s processing is discussed; we also introduce the synchronization between the hardware and the software, and use the DAQ board’s hardware digital trigger to start the signal acquisition. We use the classical numerical analytical method to process the signal data and display it in many ways. You can save the signal data at any time and store it to database. This software is the base software and provides the processing method for the optical biopsy, especially the localization of early nasopharyngeal carcinoma.To test the synchronization of signal acquisition and the accuracy of the wavelength calibration, we design the synchronization testing experiment. The result demonstrates that the software which we design has a good accuracy of the wavelength calibration and the synchronization between the hardware and the software, the performance of the whole system works well. It also has a powerful analysis and display function. The system is conveniently to be used, and it shows promise for developing the optical biopsy technology of early nasopharyngeal carcinoma.更多还原