【作者】 韩文忠；

【导师】 周亚滨；

【作者基本信息】 黑龙江中医药大学 ， 中西医结合临床， 2005， 硕士

【摘要】 目的:观察注射用刺五加(冻干粉针)治疗气虚血瘀型冠心病心绞痛患者的疗效,并探讨其作用机制,为临床应用提供科学依据。 方法:采用随机、单盲、平行、对照的方法,将60例气虚血瘀型冠心病心绞痛分为试验组(注射用刺五加组)和对照组(刺五加注射液组),分别对证侯、心电图、血流变学、血清一氧化氮含量及一氧化氮合酶活性的变化进行观察。 结果:注射用刺五加可明显改善气虚血瘀型冠心病心绞痛患者临床症状、心电图、血流变学等,并可升高患者一氧化氮的含量,增强一氧化氮合酶活性。 结论:注射用刺五加对气虚血瘀型冠心病心绞痛具有较好疗效,升高一氧化氮的含量与增强一氧化氮合酶的活性,可能是其治疗冠心病心绞痛的机制之一。更多还原

【Abstract】 OBJECTIVE:To study the effect and mechanism of angina pectoris treated by sentcosus harms freed-dry injection.METHOD:60 patients with angina pectoris(the type of qi deficiency and blood stasis)were divided into treating groop with sentcosus harms freed-dry injection and control groop with sentcosus harms injection. A randomized、 single-blind、 parallel、 antitheses method was used in the observation.Changes of the symptoms,the syndromes of traditional medicine、 ECG、 blood rheology、 serum Notric oxide and serum nitric oxide synthasis of patients were recorded.RESULT:The sentcosus harms freed dry injection can relieave the symptoms of Angina Pectoris and the syndrome of traditional medicine,recover ECG and blood rheology.increase the NO and NOS serum concentration of patients. CONCLUSION:The sentcosus harms freed-dry injection in treating angina pectoris is effective.One of itsmechanisms is increasing serum NO and NOS concentration更多还原