【作者】 秦兆江；

【导师】 梁沛华；

【作者基本信息】 广州中医药大学 ， 中医外科学， 2005， 硕士

【摘要】 目的 探索男性不育症患者不同中医证型和精浆中性α—葡萄糖苷酶测量值之间的相互关系,为男性不育中医证型提供客观的实验室指标。 方法 选择符合男性不育症诊断和中医辨证标准的男性已婚患者117例纳入本研究。根据中医辨证分型标准将研究对象分为肾阳虚证23例、肾阴虚证22例、痰湿内蕴证20例、肝郁血瘀证24例、湿热下注28例。对所有受检者采集的精液进行精浆中性α—葡萄糖苷酶定量测量并进行计算机辅助精子质量分析(CASA)。所有数据用SPSS 11.0软件处理,结果以均数±标准差(X±S)表示。计量资料采用t检验以及One-Way ANOVA检验,计数资料采用卡方(X~2)检验。 结果 所有117例男性不育症患者中,精浆中性α—葡萄糖苷酶测量值在异常范围内占80.34%,正常者占19.66%。在五种基本中医证型的分布通过One-Way ANOVA检验,均有p>0.05,即两两中医证型之间比较,均无统计学差异。 结论 精浆中性α—葡萄糖苷酶测量指标虽然可以对不育症诊断提供可靠的证据,尚不能作为中医辨证分型的微观指标。更多还原

【Abstract】 Objective: Study the interrelation between different syndrome patterns of Traditional Chinese Medicine in male sterility sufferers and seminal plasma neutral α -glucosidase measured value. Also to provide an objectivity reference lab index for syndrome pattern of TCM in male sterility sufferers.Method: We select 117 married male patients which comply to the study requirements. We divide these cases into five groups according to the standard of differentiation of symptoms and signs for classification of syndrome. These groups are: deficiency of kidney-YANG (23cases) ;deficiency of kidney-YIN (22cases) ;phlegmatic hygrosis (20cases) ;stagnation of liver-QI and blood stasis (24cases) ; damp invasion of lower energizer (28cases) .We carry on measuring seminal plasma neutral α —glucosidase and CASA in semen collected by the subjects. All data is treated with SPSS 11.0 software and the result is expressed with mean ± standard deviation (X ± S). Measurement data is treated with the t-test and the One—Way ANOVA test and enumeration data is treated with the chi-square test.Effect: There are 80.34% within the abnormity scope. The remaining 19.66 % is within normal scope about the measured value of seminal plasma neutral a —glucosidase out of 117male sterility sufferers The distribution of the basic syndrome pattern of TCM through One—Way ANOVA test has no statistical difference(p>0.05).Conclusion: Seminal plasma neutral α —glucosidase measured value can provide reliable evidence for diagnosing male sterility. However it can not be a micro index of differentiation of symptoms and signs for classification of syndrome.更多还原