【作者】 李玉峰；

【导师】 王林斗；

【作者基本信息】 天津大学 ， 通信与信息系统， 2004， 硕士

【摘要】 青光眼是种被称为“潜伏杀手”的致盲眼病。为此，许多国家，特别是美、日等发达国家，开展了对眼压测量技术的研究工作。目前国内外采用的眼压测量技术普遍采用接触测量法，但是这种眼压测量方法，病人痛苦需麻醉，而且极易因此带来病人之间的交叉感染，使用不方便。于是现在许多国家开始竞相研究非接触眼压测量技术，但是根据这些技术制成的眼压计仪器设备复杂、造价昂贵、使用上有条件限制，至今尚未普及。为了设计出测量精度高、造价低、使用方便、体积小巧的眼压计，本论文中设计了一种新的非接触眼压测量系统：激光干涉式非接触眼压测量系统，它主要是利用激光干涉原理这种精密的测量方法对眼压进行测量。采用这种方法病人无痛苦，不会产生交叉感染，同时又勿需眼角膜有较大形变。另外，在测量中采用的入射光依据卫生组织指定的安全标准，光强非常微弱，经过实验证明对人眼不会带来任何不良反应。本眼压测量系统以８０５１单片机为主控制系统，主要用来控制其他部分协调工作，如液晶显示、脉冲发生、脉冲计数；脉冲气流发生器是这个眼压测量系统设计中的一个难点和重点，我们通过CPLD实现脉冲分配，然后驱动步进电机产生运动，从而推进活塞产生脉冲气流，性能稳定可靠；电信息处理电路的设计难点在于因为入射到光电检测器的光信号非常微弱，只有10-6~10-9W量级，我们通过大量实验设计出一种新的光电检测电路结构，不但降低了噪声而且对光电转换后有用的电信号进行了适当的放大；电信息处理系统中有源带通滤波器部分对光电检测系统中带外噪声可以很好滤除，有源带通滤波器采用椭圆函数型滤波器对系统性能有很大的改善作用；最后对整体系统进行了性能测试和结果分析，实验结果表明：用激光干涉式非接触眼压测量系统测量眼压这一方案是可行的，而且正在逐渐走向成熟。由于本课题是国家自然科学基金项目的内容，所以本课题的完成为该自然科学基金项目的完成打下了基础。更多还原

【Abstract】 Glaucoma is one disease which can make the eye be blind, often called “lurk killer”. For these reason, many developed country, especially US and Japan had done some research work on intraocular pressure(IOP) measurement. Now, the people widely adopt the contact measurements, but these kinds of measurement make the patient uncomfortable, and the patient need anaesthesia. At the same time, it can bring the infection among the patient. It is very un-convenient. Due to this, many country had developed some non-contact measuring technologies, but the instruments based on these technologies are very complex, costliness and restrained. In order to research the instrument which has the advantages of high precision, simple configuration, low cost and convenient for popularization, we had designed a new measuring system: the non-contact measuring system based on the interferential laser. It mainly based on interferential laser fine technology which can reduce pain and infection, and could not make intraocular heavily shaped. Besides the laser we used is very faint which could not make damages to our eyes, and had been tested could not make uncomfortable, according to the standard of sanitation organization. In this measuring system design, we use 8051 MCU as main control part that can harmonize other parts, such as LCD display, pulse generating and pulse counting; pulse stream generator design is a key and hard technology in this system design. We use CPLD as pulse distributor so that motor movement can drive piston pout pulse stream, and the above design had been tested has good performance. The difficulty of the electronic system design lies in the laser is very faint for being photodetected, known as 10-6~10-9W.After lots of test, we bring forward a new design of the photoelectricity system, it has the advantages of both reduce the noise and magnify the signal. Among this, ellipse type filter can reduce the beyond band noise very well. At last, through the performance test and results analysis, primary experimental results indicates that the project useing the method of non-contact IOP measurement based on laser interference to measure IOP should be feasible, and are <WP=4>turning into mature. This task is the content of the project sponsored by Nation Natural Science Foundation, therefore, To solve this task well is the basis of the accomplishment of the project sponsored by Nation Natural Science Foundation.更多还原