聚β-羟基丁酸酯的纺丝成型工艺研究

【作者】 艾莉；

【导师】 杨青芳；

【作者基本信息】 西北工业大学 ， 材料学， 2004， 硕士

【摘要】 本文通过加入含量低于20％的高分子量聚氧乙烯(PEO)对聚β-羟基丁酸酯(PHB)共混改性，经红外光谱仪(IR)、示差扫描量热计(DSC)分析和力学性能测试表明，改性后材料中的聚β-羟基丁酸酯的分子结构没有变化，但是使聚β-羟基丁酸酯的韧性和加工工艺性得到了改善。然后采用干法纺丝对改性后的聚β-羟基丁酸酯进行了纺丝工艺的研究。通过研究分析在不同纺丝工艺参数下制得纤维的拉伸断裂强度、断裂延伸率和结结强度等力学性能的变化，并用扫描电子显微镜(SEM)和偏光显微镜(OPM)对纤维的表面形态进行了表征，确定了最佳的纺丝工艺条件。在此基础上，采用动物体内实验和体外实验，进一步分析研究了纤维的生物相容性和生物降解性。实验结果表明，采用干法纺丝工艺制备的聚β-羟基丁酸酯纤维具有一定的韧性、强度和良好的生物相容性与生物降解性，实验中还发现聚氧乙烯的加入可以使聚β-羟基丁酸酯的降解速度加快。更多还原

【Abstract】 In this paper, the modification of PHB by blending PEO which content is less than 20% is studied firstly. Through FT-IR, DSC analysis and the mechanical properties test of PHB/PEO, the molecular structure of PHB in this material was not changed but the toughness and technological property of this material was improved. Then study on the spinning technology of PHB/PEO by the dry spinning. Through synthesizing the change of intensity, elongation and other mechanical properties, and characterizing the surface configuration of fiber produced under different condition with SEM and OPM, the best spinning technology was confirmed. On this basis, the biocompatibility and degradation of the fibers were synthesized by experiment in vitro and in vivo. Experimental result showed that PHB fibers produced by dry spinning have some toughness, strength and good biocompatibility and good biodegradability. And also addition of PEO can accelerate the biodegradation of PHB.更多还原